Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366771248> ?p ?o ?g. }
- W4366771248 endingPage "1424" @default.
- W4366771248 startingPage "1424" @default.
- W4366771248 abstract "Small size in mammals usually restricts long-term, frequent monitoring of endocrine function using plasma as a matrix. Thus, the non-invasive monitoring of hormone metabolite concentrations in excreta may provide an invaluable approach. The aim of the current study was to examine the suitability of enzyme immunoassays (EIAs) for monitoring responses to stressors in the naked mole-rat (Heterocephalus glaber, NMR) using urine and feces as hormone matrices. A saline control administration, and a high- and low-dose adrenocorticotropic hormone (ACTH) challenge were performed on six male and six female disperser morph NMRs. The results revealed that a 5α-pregnane-3β,11β,21-triol-20-one EIA detecting glucocorticoid metabolites (GCMs) with a 5α-3β-11β-diol structure is the most suitable assay for measuring concentrations in male urine samples, whereas an 11-oxoaetiocholanolone EIA detecting GCMs with a 5β-3α-ol-11-one structure appears the most suitable EIA for quantifying GCMs in female urine. An 11-oxoaetiocholanolone EIA detecting 11,17 dioxoandrostanes was the most suitable EIA for quantifying GCMs in the feces of both sexes. There were sex-related differences in response to the high- and low-dose ACTH challenge. We recommend using feces as a more suitable matrix for non-invasive GCM monitoring for NMRs which can be valuable when investigating housing conditions and other welfare aspects." @default.
- W4366771248 created "2023-04-25" @default.
- W4366771248 creator A5010435984 @default.
- W4366771248 creator A5013552744 @default.
- W4366771248 creator A5016168669 @default.
- W4366771248 creator A5045390769 @default.
- W4366771248 creator A5076015573 @default.
- W4366771248 date "2023-04-21" @default.
- W4366771248 modified "2023-10-01" @default.
- W4366771248 title "Validation of Enzyme Immunoassays via an Adrenocorticotrophic Stimulation Test for the Non-Invasive Quantification of Stress-Related Hormone Metabolites in Naked Mole-Rats" @default.
- W4366771248 cites W124877993 @default.
- W4366771248 cites W1493562038 @default.
- W4366771248 cites W1581988486 @default.
- W4366771248 cites W1951724000 @default.
- W4366771248 cites W1965486589 @default.
- W4366771248 cites W1965938508 @default.
- W4366771248 cites W1972853535 @default.
- W4366771248 cites W1975745651 @default.
- W4366771248 cites W1978164329 @default.
- W4366771248 cites W1997702463 @default.
- W4366771248 cites W2001676343 @default.
- W4366771248 cites W2005638112 @default.
- W4366771248 cites W2005976598 @default.
- W4366771248 cites W2011027148 @default.
- W4366771248 cites W2036674007 @default.
- W4366771248 cites W2042341881 @default.
- W4366771248 cites W2042588288 @default.
- W4366771248 cites W2056334583 @default.
- W4366771248 cites W2068115451 @default.
- W4366771248 cites W2068943579 @default.
- W4366771248 cites W2072631898 @default.
- W4366771248 cites W2097499286 @default.
- W4366771248 cites W2119432249 @default.
- W4366771248 cites W2130097342 @default.
- W4366771248 cites W2132539548 @default.
- W4366771248 cites W2136091506 @default.
- W4366771248 cites W2166981541 @default.
- W4366771248 cites W2168394255 @default.
- W4366771248 cites W2169811566 @default.
- W4366771248 cites W2172048140 @default.
- W4366771248 cites W2179580825 @default.
- W4366771248 cites W2406634442 @default.
- W4366771248 cites W2547759350 @default.
- W4366771248 cites W2751832357 @default.
- W4366771248 cites W2901528734 @default.
- W4366771248 cites W2905235316 @default.
- W4366771248 cites W2912840571 @default.
- W4366771248 cites W2962199990 @default.
- W4366771248 cites W3000079749 @default.
- W4366771248 cites W3007327966 @default.
- W4366771248 cites W3014240661 @default.
- W4366771248 cites W3014345288 @default.
- W4366771248 cites W3031015741 @default.
- W4366771248 cites W3167628703 @default.
- W4366771248 cites W3210196098 @default.
- W4366771248 cites W4220723815 @default.
- W4366771248 cites W4280517526 @default.
- W4366771248 cites W4302275739 @default.
- W4366771248 cites W4307350851 @default.
- W4366771248 cites W4316806156 @default.
- W4366771248 cites W45333436 @default.
- W4366771248 doi "https://doi.org/10.3390/ani13081424" @default.
- W4366771248 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37106986" @default.
- W4366771248 hasPublicationYear "2023" @default.
- W4366771248 type Work @default.
- W4366771248 citedByCount "0" @default.
- W4366771248 crossrefType "journal-article" @default.
- W4366771248 hasAuthorship W4366771248A5010435984 @default.
- W4366771248 hasAuthorship W4366771248A5013552744 @default.
- W4366771248 hasAuthorship W4366771248A5016168669 @default.
- W4366771248 hasAuthorship W4366771248A5045390769 @default.
- W4366771248 hasAuthorship W4366771248A5076015573 @default.
- W4366771248 hasBestOaLocation W43667712481 @default.
- W4366771248 hasConcept C126322002 @default.
- W4366771248 hasConcept C134018914 @default.
- W4366771248 hasConcept C185592680 @default.
- W4366771248 hasConcept C18903297 @default.
- W4366771248 hasConcept C2777477808 @default.
- W4366771248 hasConcept C2780026642 @default.
- W4366771248 hasConcept C2780546910 @default.
- W4366771248 hasConcept C2780841215 @default.
- W4366771248 hasConcept C46699223 @default.
- W4366771248 hasConcept C61716771 @default.
- W4366771248 hasConcept C71315377 @default.
- W4366771248 hasConcept C71924100 @default.
- W4366771248 hasConcept C86803240 @default.
- W4366771248 hasConceptScore W4366771248C126322002 @default.
- W4366771248 hasConceptScore W4366771248C134018914 @default.
- W4366771248 hasConceptScore W4366771248C185592680 @default.
- W4366771248 hasConceptScore W4366771248C18903297 @default.
- W4366771248 hasConceptScore W4366771248C2777477808 @default.
- W4366771248 hasConceptScore W4366771248C2780026642 @default.
- W4366771248 hasConceptScore W4366771248C2780546910 @default.
- W4366771248 hasConceptScore W4366771248C2780841215 @default.
- W4366771248 hasConceptScore W4366771248C46699223 @default.
- W4366771248 hasConceptScore W4366771248C61716771 @default.
- W4366771248 hasConceptScore W4366771248C71315377 @default.
- W4366771248 hasConceptScore W4366771248C71924100 @default.