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- W4366772783 abstract "PURPOSE: Peripheral artery disease (PAD) can have detrimental impacts on wound healing. Negative pressure wound therapy (NPWT) has demonstrated effectiveness for open wounds, but its effectiveness on closed wounds remains unclear. The study aim was to compare the rate of wound complications when using NPWT on post-amputation closed incisions versus standard dry dressing. METHODS: Patients were randomized into two cohorts of postoperative closed incisional dressing. Cohort A received the standard dry dressing. Group B received Foam, Drape, and PrevenaTM. The device was placed over the closed incision, with negative pressure set to 125mmHG. Wound complications were assessed at 5-days, 30-days, and 90-days postoperative. RESULTS: Of the 108 patients enrolled, 47 patients (43.5%) did not complete the study. Data was analyzed for the remaining 30 patients who received dry dressing and 31 in the NPWT group. There were no demographic differences between cohorts. The dry dressing group had significantly higher rates of ESRD (40% vs. 12.9%), PAD (66.7% vs. 19.4%), PVD (60% vs. 19.4%), and CAD (26.7% vs. 6.5%). Amputation type was similar between groups. No difference in rates of wound complications was observed between the PrevenaTM and dry dressing groups at all postoperative time points. CONCLUSION: Overall, our data suggests that novel NPWT placement on closed incisions post-amputation does not significantly reduce wound complications when compared to standard of care." @default.
- W4366772783 created "2023-04-25" @default.
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- W4366772783 date "2023-04-01" @default.
- W4366772783 modified "2023-09-27" @default.
- W4366772783 title "D13. A Randomized Controlled Trial Evaluating the Outcomes for Closed Incision Negative Pressure Wound Therapy for Non-traumatic Lower Extremity Amputations: A Pilot Study" @default.
- W4366772783 doi "https://doi.org/10.1097/01.gox.0000934664.21126.4a" @default.
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