Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366773580> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W4366773580 abstract "Enabling (radical-type) nitrene transfer reactions in water can open up a wide range of (novel) applications, such as the in vivo synthesis of medicines. However, these reactions typically suffer from oxygen-containing side-product formation, of which the origin is not fully understood. Therefore, we investigated aqueous styrene aziridination using a water-soluble [CoIII(TAMLred)]– catalyst known to be active in radical-type nitrene transfer in organic solvents. The cobalt-catalyzed aziridination of styrene in water (pH = 7) yielded styrene oxide as the major product, next to minor amounts of aziridine product. Based on 18O-labeling studies, catalysis and mass spectrometry experiments, we demonstrated that styrene oxide formation proceeds via hydrolysis of the formed nitrene radical complexes. Computational studies support that this process is facile and yields oxyl radical complexes active in oxygen atom transfer to styrene. Based on these mechanistic insights, the pH was adjusted to afford selective aziridination in water." @default.
- W4366773580 created "2023-04-25" @default.
- W4366773580 creator A5002924841 @default.
- W4366773580 creator A5013850715 @default.
- W4366773580 creator A5021283178 @default.
- W4366773580 creator A5029252935 @default.
- W4366773580 creator A5054423473 @default.
- W4366773580 creator A5064830068 @default.
- W4366773580 creator A5068995354 @default.
- W4366773580 date "2023-04-21" @default.
- W4366773580 modified "2023-09-26" @default.
- W4366773580 title "Styrene Aziridination with [Co^III(TAML^red)]– in Water; Understanding and Preventing Epoxidation via Nitrene Hydrolysis" @default.
- W4366773580 doi "https://doi.org/10.26434/chemrxiv-2022-0rw6q-v2" @default.
- W4366773580 hasPublicationYear "2023" @default.
- W4366773580 type Work @default.
- W4366773580 citedByCount "0" @default.
- W4366773580 crossrefType "posted-content" @default.
- W4366773580 hasAuthorship W4366773580A5002924841 @default.
- W4366773580 hasAuthorship W4366773580A5013850715 @default.
- W4366773580 hasAuthorship W4366773580A5021283178 @default.
- W4366773580 hasAuthorship W4366773580A5029252935 @default.
- W4366773580 hasAuthorship W4366773580A5054423473 @default.
- W4366773580 hasAuthorship W4366773580A5064830068 @default.
- W4366773580 hasAuthorship W4366773580A5068995354 @default.
- W4366773580 hasBestOaLocation W43667735801 @default.
- W4366773580 hasConcept C150539798 @default.
- W4366773580 hasConcept C15920480 @default.
- W4366773580 hasConcept C161790260 @default.
- W4366773580 hasConcept C178790620 @default.
- W4366773580 hasConcept C185592680 @default.
- W4366773580 hasConcept C188027245 @default.
- W4366773580 hasConcept C21951064 @default.
- W4366773580 hasConcept C2776186722 @default.
- W4366773580 hasConcept C2777566558 @default.
- W4366773580 hasConcept C2778544067 @default.
- W4366773580 hasConcept C2780378348 @default.
- W4366773580 hasConcept C38489247 @default.
- W4366773580 hasConcept C44228677 @default.
- W4366773580 hasConcept C521977710 @default.
- W4366773580 hasConcept C75473681 @default.
- W4366773580 hasConcept C94412978 @default.
- W4366773580 hasConceptScore W4366773580C150539798 @default.
- W4366773580 hasConceptScore W4366773580C15920480 @default.
- W4366773580 hasConceptScore W4366773580C161790260 @default.
- W4366773580 hasConceptScore W4366773580C178790620 @default.
- W4366773580 hasConceptScore W4366773580C185592680 @default.
- W4366773580 hasConceptScore W4366773580C188027245 @default.
- W4366773580 hasConceptScore W4366773580C21951064 @default.
- W4366773580 hasConceptScore W4366773580C2776186722 @default.
- W4366773580 hasConceptScore W4366773580C2777566558 @default.
- W4366773580 hasConceptScore W4366773580C2778544067 @default.
- W4366773580 hasConceptScore W4366773580C2780378348 @default.
- W4366773580 hasConceptScore W4366773580C38489247 @default.
- W4366773580 hasConceptScore W4366773580C44228677 @default.
- W4366773580 hasConceptScore W4366773580C521977710 @default.
- W4366773580 hasConceptScore W4366773580C75473681 @default.
- W4366773580 hasConceptScore W4366773580C94412978 @default.
- W4366773580 hasLocation W43667735801 @default.
- W4366773580 hasOpenAccess W4366773580 @default.
- W4366773580 hasPrimaryLocation W43667735801 @default.
- W4366773580 hasRelatedWork W1964387624 @default.
- W4366773580 hasRelatedWork W1970786813 @default.
- W4366773580 hasRelatedWork W2089608599 @default.
- W4366773580 hasRelatedWork W2315074163 @default.
- W4366773580 hasRelatedWork W2320403388 @default.
- W4366773580 hasRelatedWork W2380426762 @default.
- W4366773580 hasRelatedWork W2383113321 @default.
- W4366773580 hasRelatedWork W2556676125 @default.
- W4366773580 hasRelatedWork W2975184688 @default.
- W4366773580 hasRelatedWork W3003237812 @default.
- W4366773580 isParatext "false" @default.
- W4366773580 isRetracted "false" @default.
- W4366773580 workType "article" @default.