Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366775584> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W4366775584 endingPage "71" @default.
- W4366775584 startingPage "70" @default.
- W4366775584 abstract "PURPOSE: Breast cancer related lymphedema (BCRL) may be prevented with immediate lymphatic reconstruction (ILR). However, prioritizing patients for ILR based on risk is not possible since current predictive models include obscure datapoints and omit key risk factors. The purpose of this study was to create a simple predictive model for BCRL. METHODS: A prospective cohort of patients treated for breast cancer with either ALND or SLNB and followed with arm volume measurements was used to develop two predictive models via logistic regression: a preoperative model (model 1) and a postoperative model (model 2). Model 1 was externally validated using a cohort of 34,438 patients with an ICD diagnosis of breast cancer. RESULTS: The prospective cohort consisted of 1,882 patients with an 11.6% rate of BCRL at an average follow-up of 3.9 (SD 1.8) years. Model 1 included: age, weight, height, race, ALND or SLNB, any radiation therapy, and any chemotherapy. Model 2 included: age, weight, ALND or SLNB, any chemotherapy, and current arm swelling. Accuracy was 75.0% for model 1 (sensitivity 71.6%, specificity 75.4%, AUC 78.9%) and 87.7% for model 2 (sensitivity 66.1%, specificity 90.5%, AUC 85.7%) at a cutoff of 19.0%. Both models demonstrated high AUCs on external (model 1, 71.4%) or internal (model 2, 82.5%) validation. CONCLUSION: Preoperative and postoperative prediction models for BCRL can be highly accurate and clinically-relevant tools comprised of inputs that are easily accessible to patients and providers. These models should be used to identify at-risk patients for perioperative risk reduction measures and surveillance." @default.
- W4366775584 created "2023-04-25" @default.
- W4366775584 creator A5000412520 @default.
- W4366775584 creator A5000684834 @default.
- W4366775584 creator A5028112952 @default.
- W4366775584 creator A5049468226 @default.
- W4366775584 creator A5069254777 @default.
- W4366775584 creator A5081956660 @default.
- W4366775584 creator A5091493220 @default.
- W4366775584 date "2023-04-01" @default.
- W4366775584 modified "2023-09-30" @default.
- W4366775584 title "D18. Risk of Breast Cancer-Related Lymphedema: Development and Validation of a Clinically-Relevant, Patient-facing Prediction Model" @default.
- W4366775584 doi "https://doi.org/10.1097/01.gox.0000934684.25197.89" @default.
- W4366775584 hasPublicationYear "2023" @default.
- W4366775584 type Work @default.
- W4366775584 citedByCount "0" @default.
- W4366775584 crossrefType "journal-article" @default.
- W4366775584 hasAuthorship W4366775584A5000412520 @default.
- W4366775584 hasAuthorship W4366775584A5000684834 @default.
- W4366775584 hasAuthorship W4366775584A5028112952 @default.
- W4366775584 hasAuthorship W4366775584A5049468226 @default.
- W4366775584 hasAuthorship W4366775584A5069254777 @default.
- W4366775584 hasAuthorship W4366775584A5081956660 @default.
- W4366775584 hasAuthorship W4366775584A5091493220 @default.
- W4366775584 hasBestOaLocation W43667755841 @default.
- W4366775584 hasConcept C121332964 @default.
- W4366775584 hasConcept C121608353 @default.
- W4366775584 hasConcept C126322002 @default.
- W4366775584 hasConcept C141071460 @default.
- W4366775584 hasConcept C143998085 @default.
- W4366775584 hasConcept C151956035 @default.
- W4366775584 hasConcept C188816634 @default.
- W4366775584 hasConcept C2778217198 @default.
- W4366775584 hasConcept C2781392513 @default.
- W4366775584 hasConcept C530470458 @default.
- W4366775584 hasConcept C62520636 @default.
- W4366775584 hasConcept C71924100 @default.
- W4366775584 hasConcept C72563966 @default.
- W4366775584 hasConceptScore W4366775584C121332964 @default.
- W4366775584 hasConceptScore W4366775584C121608353 @default.
- W4366775584 hasConceptScore W4366775584C126322002 @default.
- W4366775584 hasConceptScore W4366775584C141071460 @default.
- W4366775584 hasConceptScore W4366775584C143998085 @default.
- W4366775584 hasConceptScore W4366775584C151956035 @default.
- W4366775584 hasConceptScore W4366775584C188816634 @default.
- W4366775584 hasConceptScore W4366775584C2778217198 @default.
- W4366775584 hasConceptScore W4366775584C2781392513 @default.
- W4366775584 hasConceptScore W4366775584C530470458 @default.
- W4366775584 hasConceptScore W4366775584C62520636 @default.
- W4366775584 hasConceptScore W4366775584C71924100 @default.
- W4366775584 hasConceptScore W4366775584C72563966 @default.
- W4366775584 hasIssue "4S" @default.
- W4366775584 hasLocation W43667755841 @default.
- W4366775584 hasOpenAccess W4366775584 @default.
- W4366775584 hasPrimaryLocation W43667755841 @default.
- W4366775584 hasRelatedWork W2081872483 @default.
- W4366775584 hasRelatedWork W2245189862 @default.
- W4366775584 hasRelatedWork W2320704340 @default.
- W4366775584 hasRelatedWork W2326652567 @default.
- W4366775584 hasRelatedWork W2330499080 @default.
- W4366775584 hasRelatedWork W2410365430 @default.
- W4366775584 hasRelatedWork W3112166790 @default.
- W4366775584 hasRelatedWork W3125823570 @default.
- W4366775584 hasRelatedWork W377899687 @default.
- W4366775584 hasRelatedWork W2100228880 @default.
- W4366775584 hasVolume "11" @default.
- W4366775584 isParatext "false" @default.
- W4366775584 isRetracted "false" @default.
- W4366775584 workType "article" @default.