Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366827178> ?p ?o ?g. }
- W4366827178 endingPage "1251" @default.
- W4366827178 startingPage "1251" @default.
- W4366827178 abstract "Multisystem inflammatory syndrome in children (MIS-C) is an immune-mediated complication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Cardiovascular system is commonly involved. Acute heart failure (AHF) is the most severe complication of MIS-C, leading to cardiogenic shock. The aim of the study was to characterise the course of MIS-C with a focus on cardiovascular involvement, based on echocardiographic (echo) evaluation, in 498 children (median age 8.3 years, 63% boys) hospitalised in 50 cities in Poland. Among them, 456 (91.5%) had cardiovascular system involvement: 190 (48.2%) of patients had (most commonly atrioventricular) valvular insufficiency, 155 (41.0%) had contractility abnormalities and 132 (35.6%) had decreased left ventricular ejection fraction (LVEF < 55%). Most of these abnormalities improved within a few days. Analysis of the results obtained from two echo descriptions (a median of 5 days apart) revealed a >10% increase in LVEF even in children with primarily normal LVEF. Lower levels of lymphocytes, platelets and sodium and higher levels of inflammatory markers on admission were significantly more common among older children with contractility dysfunction, while younger children developed coronary artery abnormality (CAA) more often. The incidence of ventricular dysfunction might be underestimated. The majority of children with AHF improved significantly within a few days. CAAs were relatively rare. Children with impaired contractility as well as other cardiac abnormalities differed significantly from children without such conditions. Due to the exploratory nature of this study, these findings should be confirmed in further studies." @default.
- W4366827178 created "2023-04-25" @default.
- W4366827178 creator A5004659933 @default.
- W4366827178 creator A5011720701 @default.
- W4366827178 creator A5028075236 @default.
- W4366827178 creator A5054292652 @default.
- W4366827178 creator A5083365708 @default.
- W4366827178 date "2023-04-23" @default.
- W4366827178 modified "2023-10-16" @default.
- W4366827178 title "Cardiac Involvement in Patients with Multisystem Inflammatory Syndrome in Children (MIS-C) in Poland" @default.
- W4366827178 cites W2071490381 @default.
- W4366827178 cites W2076313335 @default.
- W4366827178 cites W2604027935 @default.
- W4366827178 cites W2996184269 @default.
- W4366827178 cites W3007940623 @default.
- W4366827178 cites W3009828712 @default.
- W4366827178 cites W3012747666 @default.
- W4366827178 cites W3013231340 @default.
- W4366827178 cites W3013648910 @default.
- W4366827178 cites W3013949914 @default.
- W4366827178 cites W3016535995 @default.
- W4366827178 cites W3022160993 @default.
- W4366827178 cites W3024521558 @default.
- W4366827178 cites W3024822200 @default.
- W4366827178 cites W3032913111 @default.
- W4366827178 cites W3033853571 @default.
- W4366827178 cites W3033880976 @default.
- W4366827178 cites W3034016318 @default.
- W4366827178 cites W3036057410 @default.
- W4366827178 cites W3037922663 @default.
- W4366827178 cites W3038003713 @default.
- W4366827178 cites W3041306292 @default.
- W4366827178 cites W3041825924 @default.
- W4366827178 cites W3042886141 @default.
- W4366827178 cites W3045195423 @default.
- W4366827178 cites W3046688875 @default.
- W4366827178 cites W3047926481 @default.
- W4366827178 cites W3081203463 @default.
- W4366827178 cites W3082441171 @default.
- W4366827178 cites W3083424448 @default.
- W4366827178 cites W3084924559 @default.
- W4366827178 cites W3085201079 @default.
- W4366827178 cites W3087850009 @default.
- W4366827178 cites W3089911709 @default.
- W4366827178 cites W3090065478 @default.
- W4366827178 cites W3103680708 @default.
- W4366827178 cites W3105775294 @default.
- W4366827178 cites W3112363486 @default.
- W4366827178 cites W3120305145 @default.
- W4366827178 cites W3135665874 @default.
- W4366827178 cites W3167287181 @default.
- W4366827178 cites W3179373143 @default.
- W4366827178 cites W3184364507 @default.
- W4366827178 cites W3188184560 @default.
- W4366827178 cites W3200240687 @default.
- W4366827178 cites W4200361524 @default.
- W4366827178 cites W4200514710 @default.
- W4366827178 cites W4210944344 @default.
- W4366827178 cites W4213187554 @default.
- W4366827178 cites W4214743988 @default.
- W4366827178 cites W4224300725 @default.
- W4366827178 cites W4225395010 @default.
- W4366827178 cites W4226333036 @default.
- W4366827178 cites W4280558799 @default.
- W4366827178 cites W4309765780 @default.
- W4366827178 cites W4311035620 @default.
- W4366827178 cites W4313590662 @default.
- W4366827178 doi "https://doi.org/10.3390/biomedicines11051251" @default.
- W4366827178 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37238922" @default.
- W4366827178 hasPublicationYear "2023" @default.
- W4366827178 type Work @default.
- W4366827178 citedByCount "1" @default.
- W4366827178 countsByYear W43668271782023 @default.
- W4366827178 crossrefType "journal-article" @default.
- W4366827178 hasAuthorship W4366827178A5004659933 @default.
- W4366827178 hasAuthorship W4366827178A5011720701 @default.
- W4366827178 hasAuthorship W4366827178A5028075236 @default.
- W4366827178 hasAuthorship W4366827178A5054292652 @default.
- W4366827178 hasAuthorship W4366827178A5083365708 @default.
- W4366827178 hasBestOaLocation W43668271781 @default.
- W4366827178 hasConcept C126322002 @default.
- W4366827178 hasConcept C164705383 @default.
- W4366827178 hasConcept C2776850375 @default.
- W4366827178 hasConcept C2777698277 @default.
- W4366827178 hasConcept C2778198053 @default.
- W4366827178 hasConcept C39133596 @default.
- W4366827178 hasConcept C500558357 @default.
- W4366827178 hasConcept C71924100 @default.
- W4366827178 hasConcept C78085059 @default.
- W4366827178 hasConcept C81182388 @default.
- W4366827178 hasConceptScore W4366827178C126322002 @default.
- W4366827178 hasConceptScore W4366827178C164705383 @default.
- W4366827178 hasConceptScore W4366827178C2776850375 @default.
- W4366827178 hasConceptScore W4366827178C2777698277 @default.
- W4366827178 hasConceptScore W4366827178C2778198053 @default.
- W4366827178 hasConceptScore W4366827178C39133596 @default.
- W4366827178 hasConceptScore W4366827178C500558357 @default.
- W4366827178 hasConceptScore W4366827178C71924100 @default.