Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366827897> ?p ?o ?g. }
- W4366827897 endingPage "7661" @default.
- W4366827897 startingPage "7661" @default.
- W4366827897 abstract "Haematological malignancies are heterogeneous groups of cancers of the bone marrow, blood or lymph nodes, and while therapeutic advances have greatly improved the lifespan and quality of life of those afflicted, many of these cancers remain incurable. The iron-dependent, lipid oxidation-mediated form of cell death, ferroptosis, has emerged as a promising pathway to induce cancer cell death, particularly in those malignancies that are resistant to traditional apoptosis-inducing therapies. Although promising findings have been published in several solid and haematological malignancies, the major drawbacks of ferroptosis-inducing therapies are efficient drug delivery and toxicities to healthy tissue. The development of tumour-targeting and precision medicines, particularly when combined with nanotechnologies, holds potential as a way in which to overcome these obstacles and progress ferroptosis-inducing therapies into the clinic. Here, we review the current state-of-play of ferroptosis in haematological malignancies as well as encouraging discoveries in the field of ferroptosis nanotechnologies. While the research into ferroptosis nanotechnologies in haematological malignancies is limited, its pre-clinical success in solid tumours suggests this is a very feasible therapeutic approach to treat blood cancers such as multiple myeloma, lymphoma and leukaemia." @default.
- W4366827897 created "2023-04-25" @default.
- W4366827897 creator A5004676114 @default.
- W4366827897 creator A5036169480 @default.
- W4366827897 creator A5039923537 @default.
- W4366827897 creator A5064393096 @default.
- W4366827897 date "2023-04-21" @default.
- W4366827897 modified "2023-10-01" @default.
- W4366827897 title "Ferroptosis in Haematological Malignancies and Associated Therapeutic Nanotechnologies" @default.
- W4366827897 cites W1535350845 @default.
- W4366827897 cites W1971714188 @default.
- W4366827897 cites W1989230986 @default.
- W4366827897 cites W1997183854 @default.
- W4366827897 cites W1999549312 @default.
- W4366827897 cites W2002490399 @default.
- W4366827897 cites W2025639892 @default.
- W4366827897 cites W2043622833 @default.
- W4366827897 cites W2047114123 @default.
- W4366827897 cites W2051925512 @default.
- W4366827897 cites W2052522978 @default.
- W4366827897 cites W2053618701 @default.
- W4366827897 cites W2058376258 @default.
- W4366827897 cites W2060209921 @default.
- W4366827897 cites W2063804160 @default.
- W4366827897 cites W2066800926 @default.
- W4366827897 cites W2066936530 @default.
- W4366827897 cites W2072074028 @default.
- W4366827897 cites W2072646319 @default.
- W4366827897 cites W2083299410 @default.
- W4366827897 cites W2099479166 @default.
- W4366827897 cites W2111807866 @default.
- W4366827897 cites W2114138419 @default.
- W4366827897 cites W2115980229 @default.
- W4366827897 cites W2118451648 @default.
- W4366827897 cites W2157255155 @default.
- W4366827897 cites W2165129832 @default.
- W4366827897 cites W2189205651 @default.
- W4366827897 cites W2236676365 @default.
- W4366827897 cites W2327686392 @default.
- W4366827897 cites W2508296626 @default.
- W4366827897 cites W2512106959 @default.
- W4366827897 cites W2517056180 @default.
- W4366827897 cites W2549428458 @default.
- W4366827897 cites W2550324626 @default.
- W4366827897 cites W2583594489 @default.
- W4366827897 cites W2597818558 @default.
- W4366827897 cites W2614441145 @default.
- W4366827897 cites W2621833341 @default.
- W4366827897 cites W2749918768 @default.
- W4366827897 cites W2762087180 @default.
- W4366827897 cites W2774391334 @default.
- W4366827897 cites W2778684355 @default.
- W4366827897 cites W2782636372 @default.
- W4366827897 cites W2789536863 @default.
- W4366827897 cites W2791360112 @default.
- W4366827897 cites W2797455782 @default.
- W4366827897 cites W2803347838 @default.
- W4366827897 cites W2804102163 @default.
- W4366827897 cites W2806249186 @default.
- W4366827897 cites W2807334922 @default.
- W4366827897 cites W2887799451 @default.
- W4366827897 cites W2890668604 @default.
- W4366827897 cites W2894196895 @default.
- W4366827897 cites W2902849569 @default.
- W4366827897 cites W2905446980 @default.
- W4366827897 cites W2905675459 @default.
- W4366827897 cites W2913137771 @default.
- W4366827897 cites W2916224930 @default.
- W4366827897 cites W2921881647 @default.
- W4366827897 cites W2924151995 @default.
- W4366827897 cites W2950920754 @default.
- W4366827897 cites W2959498392 @default.
- W4366827897 cites W2971457179 @default.
- W4366827897 cites W2972461983 @default.
- W4366827897 cites W2973378552 @default.
- W4366827897 cites W2980472864 @default.
- W4366827897 cites W2981179816 @default.
- W4366827897 cites W2986662505 @default.
- W4366827897 cites W2997725763 @default.
- W4366827897 cites W3003978563 @default.
- W4366827897 cites W3006744532 @default.
- W4366827897 cites W3015700103 @default.
- W4366827897 cites W3016345620 @default.
- W4366827897 cites W3016752163 @default.
- W4366827897 cites W3029628311 @default.
- W4366827897 cites W3030440441 @default.
- W4366827897 cites W3032123181 @default.
- W4366827897 cites W3034193580 @default.
- W4366827897 cites W3035153279 @default.
- W4366827897 cites W3035851500 @default.
- W4366827897 cites W3049455756 @default.
- W4366827897 cites W3082071662 @default.
- W4366827897 cites W3084631824 @default.
- W4366827897 cites W3091213026 @default.
- W4366827897 cites W3092090849 @default.
- W4366827897 cites W3092243476 @default.
- W4366827897 cites W3096867320 @default.
- W4366827897 cites W3097199385 @default.