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• W4366988701 abstract "Studies addressing coronavirus disease 2019 (COVID-19) in patients with hematological malignancies have reported mortality rates of up to 40%; however, included predominantly hospitalized patients.During the first year of the pandemic, we followed adult patients with hematological malignancies treated at a tertiary center in Jerusalem, Israel, who contracted COVID-19, with the aim of studying risk factors for adverse COVID-19-related outcomes. We used remote communication to track patients managed at home-isolation, and patient questioning to assess the source of COVID-19 infection, community versus nosocomial.Our series included 183 patients, median age was 62.5 years, 72% had at least one comorbidity and 39% were receiving active antineoplastic treatment. Hospitalization, critical COVID-19, and mortality rates were 32%, 12.6%, and 9.8%, respectively, remarkably lower than previously reported. Age, multiple comorbidities, and active antineoplastic treatment were significantly associated with hospitalization due to COVID-19. Treatment with monoclonal antibodies was strongly associated with both hospitalization and critical COVID-19. In older (≥60) patients not receiving active antineoplastic treatment, mortality, and severe COVID-19 rates were comparable to those of the general Israeli population. We did not detect patients that contracted COVID-19 within the Hematology Division.These findings are relevant for the future management of patients with hematological malignancies in COVID-19-affected regions." @default.
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• W4366988701 date "2023-04-24" @default.
• W4366988701 modified "2023-10-18" @default.
• W4366988701 title "Risk factors and outcomes of <scp>COVID</scp>‐19 in adult patients with hematological malignancies: A single‐center study showing lower than expected rates of hospitalization and mortality" @default.
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• W4366988701 doi "https://doi.org/10.1111/ejh.13977" @default.
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• W4366988701 hasPublicationYear "2023" @default.
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