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• W4366989295 abstract "Abstract Background and Objectives Disparities in pancreas cancer care are multifactorial, but factors are often examined in isolation. Research that integrates these factors in a single conceptual framework is lacking. We use latent class analysis (LCA) to evaluate the association between intersectionality and patterns of care and survival in patients with resectable pancreas cancer. Methods LCA was used to identify demographic profiles in resectable pancreas cancer ( n = 140 344) diagnosed from 2004 to 2019 in the National Cancer Database (NCDB). LCA‐derived patient profiles were used to identify differences in receipt of minimum expected treatment (definitive surgery), optimal treatment (definitive surgery and chemotherapy), time to treatment, and overall survival. Results Minimum expected treatment (hazard ratio [HR] 0.69, 95% confidence interval [CI]: 0.65, 0.75) and optimal treatment (HR 0.58, 95% CI: 0.55, 0.62) were associated with improved overall survival. Seven latent classes were identified based on age, race/ethnicity, and socioeconomic status (SES) attributes (zip code‐linked education and income, insurance, geography). Compared to the referent group (≥65 years + White + med/high SES), the ≥65 years + Black profile had the longest time‐to‐treatment (24 days vs. 28 days) and lowest odds of receiving minimum (odds ratio [OR] 0.67, 95% CI: 0.64, 0.71) or optimal treatment (OR 0.76, 95% CI: 0.72, 0.81). The Hispanic patient profile had the lowest median overall survival—55.3 months versus 67.5 months. Conclusions Accounting for intersectionality in the NCDB resectable pancreatic cancer patient cohort identifies subgroups at higher risk for inequities in care. LCA demonstrates that older Black patients and Hispanic patients are at particular risk for being underserved and should be prioritiz for directed interventions." @default.
• W4366989295 created "2023-04-27" @default.
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• W4366989295 date "2023-04-24" @default.
• W4366989295 modified "2023-10-17" @default.
• W4366989295 title "Identifying patient profiles of disparate care in resectable pancreas cancer using latent class analysis" @default.
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• W4366989295 doi "https://doi.org/10.1002/jso.27275" @default.
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