Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366990192> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W4366990192 endingPage "433" @default.
- W4366990192 startingPage "425" @default.
- W4366990192 abstract "Participants of health research studies such as cancer screening trials usually have better health than the target population. Data-enabled recruitment strategies might be used to help minimise healthy volunteer effects on study power and improve equity.A computer algorithm was developed to help target trial invitations. It assumes participants are recruited from distinct sites (such as different physical locations or periods in time) that are served by clusters (such as general practitioners in England, or geographical areas), and the population may be split into defined groups (such as age and sex bands). The problem is to decide the number of people to invite from each group, such that all recruitment slots are filled, healthy volunteer effects are accounted for, and equity is achieved through representation in sufficient numbers of all major societal and ethnic groups. A linear programme was formulated for this problem.The optimisation problem was solved dynamically for invitations to the NHS-Galleri trial (ISRCTN91431511). This multi-cancer screening trial aimed to recruit 140,000 participants from areas in England over 10 months. Public data sources were used for objective function weights, and constraints. Invitations were sent by sampling according to lists generated by the algorithm. To help achieve equity the algorithm tilts the invitation sampling distribution towards groups that are less likely to join. To mitigate healthy volunteer effects, it requires a minimum expected event rate of the primary outcome in the trial.Our invitation algorithm is a novel data-enabled approach to recruitment that is designed to address healthy volunteer effects and inequity in health research studies. It could be adapted for use in other trials or research studies." @default.
- W4366990192 created "2023-04-27" @default.
- W4366990192 creator A5000643578 @default.
- W4366990192 creator A5025868896 @default.
- W4366990192 creator A5043507331 @default.
- W4366990192 creator A5044899296 @default.
- W4366990192 creator A5052213299 @default.
- W4366990192 creator A5080899656 @default.
- W4366990192 date "2023-04-24" @default.
- W4366990192 modified "2023-10-01" @default.
- W4366990192 title "Dynamic data-enabled stratified sampling for trial invitations with application in NHS-Galleri" @default.
- W4366990192 cites W134516892 @default.
- W4366990192 cites W2057276737 @default.
- W4366990192 cites W2113451181 @default.
- W4366990192 cites W2118463431 @default.
- W4366990192 cites W2161990460 @default.
- W4366990192 cites W2214802907 @default.
- W4366990192 cites W2322400678 @default.
- W4366990192 cites W2322939665 @default.
- W4366990192 cites W2723723801 @default.
- W4366990192 cites W2940683302 @default.
- W4366990192 cites W3008881689 @default.
- W4366990192 cites W3174187171 @default.
- W4366990192 cites W4281955393 @default.
- W4366990192 cites W4283653334 @default.
- W4366990192 cites W4303613649 @default.
- W4366990192 cites W4309941149 @default.
- W4366990192 doi "https://doi.org/10.1177/17407745231167369" @default.
- W4366990192 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37095697" @default.
- W4366990192 hasPublicationYear "2023" @default.
- W4366990192 type Work @default.
- W4366990192 citedByCount "0" @default.
- W4366990192 crossrefType "journal-article" @default.
- W4366990192 hasAuthorship W4366990192A5000643578 @default.
- W4366990192 hasAuthorship W4366990192A5025868896 @default.
- W4366990192 hasAuthorship W4366990192A5043507331 @default.
- W4366990192 hasAuthorship W4366990192A5044899296 @default.
- W4366990192 hasAuthorship W4366990192A5052213299 @default.
- W4366990192 hasAuthorship W4366990192A5080899656 @default.
- W4366990192 hasBestOaLocation W43669901921 @default.
- W4366990192 hasConcept C137403100 @default.
- W4366990192 hasConcept C144024400 @default.
- W4366990192 hasConcept C17744445 @default.
- W4366990192 hasConcept C19165224 @default.
- W4366990192 hasConcept C199539241 @default.
- W4366990192 hasConcept C199728807 @default.
- W4366990192 hasConcept C2776768635 @default.
- W4366990192 hasConcept C2908647359 @default.
- W4366990192 hasConcept C41008148 @default.
- W4366990192 hasConcept C512399662 @default.
- W4366990192 hasConcept C6557445 @default.
- W4366990192 hasConcept C71924100 @default.
- W4366990192 hasConcept C86803240 @default.
- W4366990192 hasConcept C99454951 @default.
- W4366990192 hasConceptScore W4366990192C137403100 @default.
- W4366990192 hasConceptScore W4366990192C144024400 @default.
- W4366990192 hasConceptScore W4366990192C17744445 @default.
- W4366990192 hasConceptScore W4366990192C19165224 @default.
- W4366990192 hasConceptScore W4366990192C199539241 @default.
- W4366990192 hasConceptScore W4366990192C199728807 @default.
- W4366990192 hasConceptScore W4366990192C2776768635 @default.
- W4366990192 hasConceptScore W4366990192C2908647359 @default.
- W4366990192 hasConceptScore W4366990192C41008148 @default.
- W4366990192 hasConceptScore W4366990192C512399662 @default.
- W4366990192 hasConceptScore W4366990192C6557445 @default.
- W4366990192 hasConceptScore W4366990192C71924100 @default.
- W4366990192 hasConceptScore W4366990192C86803240 @default.
- W4366990192 hasConceptScore W4366990192C99454951 @default.
- W4366990192 hasFunder F4320319985 @default.
- W4366990192 hasIssue "4" @default.
- W4366990192 hasLocation W43669901921 @default.
- W4366990192 hasLocation W43669901922 @default.
- W4366990192 hasLocation W43669901923 @default.
- W4366990192 hasOpenAccess W4366990192 @default.
- W4366990192 hasPrimaryLocation W43669901921 @default.
- W4366990192 hasRelatedWork W15804656 @default.
- W4366990192 hasRelatedWork W2010596157 @default.
- W4366990192 hasRelatedWork W2033621154 @default.
- W4366990192 hasRelatedWork W2036821022 @default.
- W4366990192 hasRelatedWork W2176653214 @default.
- W4366990192 hasRelatedWork W2375390266 @default.
- W4366990192 hasRelatedWork W2390745362 @default.
- W4366990192 hasRelatedWork W2748952813 @default.
- W4366990192 hasRelatedWork W2899084033 @default.
- W4366990192 hasRelatedWork W4321783936 @default.
- W4366990192 hasVolume "20" @default.
- W4366990192 isParatext "false" @default.
- W4366990192 isRetracted "false" @default.
- W4366990192 workType "article" @default.