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• W4366990962 abstract "Abstract Background In this study, stent appearance in a novel silicon-based photon-counting computed tomography (Si-PCCT) prototype was compared with a conventional energy-integrating detector CT (EIDCT) system. Methods An ex vivo phantom was created, consisting of a 2% agar-water mixture, in which human-resected and stented arteries were individually embedded. Using similar technique parameters, helical scan data was acquired using a novel prototype Si-PCCT and a conventional EIDCT system at a volumetric CT dose index (CTDI vol ) of 9 mGy. Reconstructions were made at 50 2 and 150 2 mm 2 field-of-views (FOVs) using a bone kernel and adaptive statistical iterative reconstruction with 0% blending. Using a 5-point Likert scale, reader evaluations were performed on stent appearance, blooming and inter-stent visibility. Quantitative image analysis was performed on stent diameter accuracy, blooming and inter-stent distinction. Qualitative and quantitative differences between Si-PCCT and EIDCT systems were tested with a Wilcoxon signed-rank test and a paired samples t -test, respectively. Inter- and intra-reader agreement was assessed using the intraclass correlation coefficient (ICC). Results Qualitatively, Si-PCCT images were rated higher than EIDCT images at 150-mm FOV, based on stent appearance ( p = 0.026) and blooming ( p = 0.015), with a moderate inter- (ICC = 0.50) and intra-reader (ICC = 0.60) agreement. Quantitatively, Si-PCCT yielded more accurate diameter measurements ( p = 0.001), reduced blooming ( p < 0.001) and improved inter-stent distinction ( p < 0.001). Similar trends were observed for the images reconstructed at 50-mm FOV. Conclusions When compared to EIDCT, the improved spatial resolution of Si-PCCT yields enhanced stent appearance, more accurate diameter measurements, reduced blooming and improved inter-stent distinction. Key points • This study evaluated stent appearance in a novel silicon-based photon-counting computed tomography (Si-PCCT) prototype. • Compared to standard CT, Si-PCCT resulted in more accurate stent diameter measurements. • Si-PCCT also reduced blooming artefacts and improved inter-stent visibility." @default.
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• W4366990962 date "2023-04-25" @default.
• W4366990962 modified "2023-10-02" @default.
• W4366990962 title "Stent appearance in a novel silicon-based photon-counting CT prototype: ex vivo phantom study in head-to-head comparison with conventional energy-integrating CT" @default.
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• W4366990962 doi "https://doi.org/10.1186/s41747-023-00333-0" @default.
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