FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366992409> ?p ?o ?g. }

• W4366992409 endingPage "412" @default.
• W4366992409 startingPage "393" @default.
• W4366992409 abstract "This joint guideline by American Society for Radiation Oncology (ASTRO) and the European Society for Radiotherapy and Oncology (ESTRO) was initiated to review evidence and provide recommendations regarding the use of local therapy in the management of extracranial oligometastatic non-small cell lung cancer (NSCLC). Local therapy is defined as the comprehensive treatment of all known cancer-primary tumor, regional nodal metastases, and metastases-with definitive intent.ASTRO and ESTRO convened a task force to address 5 key questions focused on the use of local (radiation, surgery, other ablative methods) and systemic therapy in the management of oligometastatic NSCLC. The questions address clinical scenarios for using local therapy, sequencing and timing when integrating local with systemic therapies, radiation techniques critical for oligometastatic disease targeting and treatment delivery, and the role of local therapy for oligoprogression or recurrent disease. Recommendations were based on a systematic literature review and created using ASTRO guidelines methodology.Based on the lack of significant randomized phase 3 trials, a patient-centered, multidisciplinary approach was strongly recommended for all decision-making regarding potential treatment. Integration of definitive local therapy was only relevant if technically feasible and clinically safe to all disease sites, defined as 5 or fewer distinct sites. Conditional recommendations were given for definitive local therapies in synchronous, metachronous, oligopersistent, and oligoprogressive conditions for extracranial disease. Radiation and surgery were the only primary definitive local therapy modalities recommended for use in the management of patients with oligometastatic disease, with indications provided for choosing one over the other. Sequencing recommendations were provided for systemic and local therapy integration. Finally, multiple recommendations were provided for the optimal technical use of hypofractionated radiation or stereotactic body radiation therapy as definitive local therapy, including dose and fractionation.Presently, data regarding clinical benefits of local therapy on overall and other survival outcomes is still sparse for oligometastatic NSCLC. However, with rapidly evolving data being generated supporting local therapy in oligometastatic NSCLC, this guideline attempted to frame recommendations as a function of the quality of data available to make decisions in a multidisciplinary approach incorporating patient goals and tolerances." @default.
• W4366992409 created "2023-04-27" @default.
• W4366992409 creator A5004505157 @default.
• W4366992409 creator A5006895694 @default.
• W4366992409 creator A5016567527 @default.
• W4366992409 creator A5022776597 @default.
• W4366992409 creator A5022864667 @default.
• W4366992409 creator A5023510680 @default.
• W4366992409 creator A5025135477 @default.
• W4366992409 creator A5025849204 @default.
• W4366992409 creator A5028299369 @default.
• W4366992409 creator A5030440776 @default.
• W4366992409 creator A5037398995 @default.
• W4366992409 creator A5050854676 @default.
• W4366992409 creator A5052958356 @default.
• W4366992409 creator A5053960294 @default.
• W4366992409 creator A5055965589 @default.
• W4366992409 creator A5060509370 @default.
• W4366992409 creator A5061500518 @default.
• W4366992409 creator A5066902959 @default.
• W4366992409 creator A5069565044 @default.
• W4366992409 creator A5077453712 @default.
• W4366992409 creator A5085912441 @default.
• W4366992409 creator A5087919687 @default.
• W4366992409 creator A5091907848 @default.
• W4366992409 date "2023-09-01" @default.
• W4366992409 modified "2023-10-17" @default.
• W4366992409 title "Treatment of Oligometastatic Non-Small Cell Lung Cancer: An ASTRO/ESTRO Clinical Practice Guideline" @default.
• W4366992409 cites W1969531640 @default.
• W4366992409 cites W1987288037 @default.
• W4366992409 cites W2030505692 @default.
• W4366992409 cites W2031688279 @default.
• W4366992409 cites W2059812828 @default.
• W4366992409 cites W2081148867 @default.
• W4366992409 cites W2084470612 @default.
• W4366992409 cites W2091461365 @default.
• W4366992409 cites W2107950705 @default.
• W4366992409 cites W2108168221 @default.
• W4366992409 cites W2127480863 @default.
• W4366992409 cites W2136706275 @default.
• W4366992409 cites W2142138307 @default.
• W4366992409 cites W2158023296 @default.
• W4366992409 cites W2394715858 @default.
• W4366992409 cites W2468996569 @default.
• W4366992409 cites W2536769127 @default.
• W4366992409 cites W2552963641 @default.
• W4366992409 cites W2564183539 @default.
• W4366992409 cites W2593002105 @default.
• W4366992409 cites W2605178884 @default.
• W4366992409 cites W2724146432 @default.
• W4366992409 cites W2761351587 @default.
• W4366992409 cites W2766071257 @default.
• W4366992409 cites W2775223042 @default.
• W4366992409 cites W2783886889 @default.
• W4366992409 cites W2796600021 @default.
• W4366992409 cites W2808354728 @default.
• W4366992409 cites W2857529534 @default.
• W4366992409 cites W2893493163 @default.
• W4366992409 cites W2893690704 @default.
• W4366992409 cites W2901734295 @default.
• W4366992409 cites W2908852422 @default.
• W4366992409 cites W2910474917 @default.
• W4366992409 cites W2914127251 @default.
• W4366992409 cites W2914135148 @default.
• W4366992409 cites W2944301866 @default.
• W4366992409 cites W2954002070 @default.
• W4366992409 cites W2958415056 @default.
• W4366992409 cites W2965638931 @default.
• W4366992409 cites W2991128853 @default.
• W4366992409 cites W2994892259 @default.
• W4366992409 cites W2997297991 @default.
• W4366992409 cites W2997721110 @default.
• W4366992409 cites W3008790677 @default.
• W4366992409 cites W3019546741 @default.
• W4366992409 cites W3032651552 @default.
• W4366992409 cites W3091771439 @default.
• W4366992409 cites W3115319505 @default.
• W4366992409 cites W3118230868 @default.
• W4366992409 cites W3130631658 @default.
• W4366992409 cites W3132144295 @default.
• W4366992409 cites W3134214345 @default.
• W4366992409 cites W3162661927 @default.
• W4366992409 cites W3172633718 @default.
• W4366992409 cites W3194779914 @default.
• W4366992409 cites W3196895583 @default.
• W4366992409 cites W3197670791 @default.
• W4366992409 cites W3206723359 @default.
• W4366992409 cites W4200190043 @default.
• W4366992409 cites W4210289312 @default.
• W4366992409 cites W4210992155 @default.
• W4366992409 cites W4212864919 @default.
• W4366992409 cites W4224235086 @default.
• W4366992409 cites W4229028961 @default.
• W4366992409 cites W4240340450 @default.
• W4366992409 cites W4281619118 @default.
• W4366992409 cites W4281634892 @default.
• W4366992409 cites W4285093714 @default.
• W4366992409 cites W4288457661 @default.

• next