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- W4366992410 abstract "Despite the successes of current coronavirus disease 2019 (COVID-19) vaccines, waning immunity, the emergence of variants of concern, and breakthrough infections among vaccinees have begun to highlight opportunities to improve vaccine platforms. Real-world vaccine efficacy studies have highlighted the reduced risk of breakthrough infections and diseases among individuals infected and vaccinated, referred to as hybrid immunity. Thus, we sought to define whether hybrid immunity shapes the humoral immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) following Pfizer/BNT162b2, Moderna mRNA-1273, ChadOx1/AZD1222, and Ad26.COV2.S vaccination. Each vaccine exhibits a unique functional humoral profile in vaccination only or hybrid immunity. However, hybrid immunity shows a unique augmentation of S2-domain-specific functional immunity that was poorly induced for the vaccination only. These data highlight the importance of natural infection in breaking the immunodominance away from the evolutionarily unstable S1 domain and potentially affording enhanced cross-variant protection by targeting the more highly conserved S2 domain of SARS-CoV-2." @default.
- W4366992410 created "2023-04-27" @default.
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- W4366992410 date "2023-05-01" @default.
- W4366992410 modified "2023-10-01" @default.
- W4366992410 title "Hybrid immunity expands the functional humoral footprint of both mRNA and vector-based SARS-CoV-2 vaccines" @default.
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- W4366992410 cites W2585172252 @default.
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- W4366992410 cites W3045933491 @default.
- W4366992410 cites W3049654234 @default.
- W4366992410 cites W3095217725 @default.
- W4366992410 cites W3096867322 @default.
- W4366992410 cites W3108610942 @default.
- W4366992410 cites W3111128314 @default.
- W4366992410 cites W3111255098 @default.
- W4366992410 cites W3111590711 @default.
- W4366992410 cites W3121906900 @default.
- W4366992410 cites W3126729284 @default.
- W4366992410 cites W3129558828 @default.
- W4366992410 cites W3130952378 @default.
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- W4366992410 cites W3171375949 @default.
- W4366992410 cites W3174017401 @default.
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- W4366992410 cites W4205483821 @default.
- W4366992410 cites W4206091204 @default.
- W4366992410 cites W4206153788 @default.
- W4366992410 cites W4206741584 @default.
- W4366992410 cites W4206914007 @default.
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- W4366992410 doi "https://doi.org/10.1016/j.xcrm.2023.101048" @default.
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- W4366992410 hasPublicationYear "2023" @default.
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