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• W4366992567 startingPage "100607" @default.
• W4366992567 abstract "Quantitative disease resistance (QDR) remains the most prevalent form of plant resistance in crop fields and wild habitats. Genome-wide association studies (GWAS) have proved to be successful in deciphering the quantitative genetic basis of complex traits such as QDR. To unravel the genetics of QDR to the devastating worldwide bacterial pathogen Ralstonia solanacearum, we performed a GWAS by challenging a highly polymorphic local mapping population of Arabidopsis thaliana with four R. solanacearum type III effector (T3E) mutants, identified as key pathogenicity determinants after a first screen on an A. thaliana core collection of 25 accessions. Although most quantitative trait loci (QTLs) were highly specific to the identity of the T3E mutant (ripAC, ripAG, ripAQ, and ripU), we finely mapped a common QTL located on a cluster of nucleotide-binding domain and leucine-rich repeat (NLR) genes that exhibited structural variation. We functionally validated one of these NLRs as a susceptibility factor in response to R. solanacearum, named it Bacterial Wilt Susceptibility 1 (BWS1), and cloned two alleles that conferred contrasting levels of QDR. Further characterization indicated that expression of BWS1 leads to suppression of immunity triggered by different R. solanacearum effectors. In addition, we showed a direct interaction between BWS1 and RipAC T3E, and BWS1 and SUPPRESSOR OF G2 ALLELE OF skp1 (SGT1b), the latter interaction being suppressed by RipAC. Together, our results highlight a putative role for BWS1 as a quantitative susceptibility factor directly targeted by the T3E RipAC, mediating negative regulation of the SGT1-dependent immune response." @default.
• W4366992567 created "2023-04-27" @default.
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• W4366992567 date "2023-09-01" @default.
• W4366992567 modified "2023-10-01" @default.
• W4366992567 title "An atypical NLR gene confers bacterial wilt susceptibility in Arabidopsis" @default.
• W4366992567 cites W1536135726 @default.
• W4366992567 cites W1592881898 @default.
• W4366992567 cites W1796198137 @default.
• W4366992567 cites W1943327251 @default.
• W4366992567 cites W1967164846 @default.
• W4366992567 cites W1972304384 @default.
• W4366992567 cites W1982459012 @default.
• W4366992567 cites W1982855075 @default.
• W4366992567 cites W1984654391 @default.
• W4366992567 cites W1985212818 @default.
• W4366992567 cites W1988178270 @default.
• W4366992567 cites W2017331330 @default.
• W4366992567 cites W2025722148 @default.
• W4366992567 cites W2046456279 @default.
• W4366992567 cites W2053245161 @default.
• W4366992567 cites W2063876459 @default.
• W4366992567 cites W2068335977 @default.
• W4366992567 cites W2071398905 @default.
• W4366992567 cites W2075139535 @default.
• W4366992567 cites W2085699671 @default.
• W4366992567 cites W2088486634 @default.
• W4366992567 cites W2097372651 @default.
• W4366992567 cites W2097928864 @default.
• W4366992567 cites W2098115340 @default.
• W4366992567 cites W2103441770 @default.
• W4366992567 cites W2106678197 @default.
• W4366992567 cites W2107303661 @default.
• W4366992567 cites W2108234281 @default.
• W4366992567 cites W2113030015 @default.
• W4366992567 cites W2116122104 @default.
• W4366992567 cites W2116439866 @default.
• W4366992567 cites W2118372805 @default.
• W4366992567 cites W2126639891 @default.
• W4366992567 cites W2128113924 @default.
• W4366992567 cites W2130753355 @default.
• W4366992567 cites W2135413308 @default.
• W4366992567 cites W2136150719 @default.
• W4366992567 cites W2139647452 @default.
• W4366992567 cites W2146856248 @default.
• W4366992567 cites W2149118179 @default.
• W4366992567 cites W2153218781 @default.
• W4366992567 cites W2154129128 @default.
• W4366992567 cites W2155943701 @default.
• W4366992567 cites W2162515800 @default.
• W4366992567 cites W2162779104 @default.
• W4366992567 cites W2266950241 @default.
• W4366992567 cites W2618971062 @default.
• W4366992567 cites W2749348568 @default.
• W4366992567 cites W2752926484 @default.
• W4366992567 cites W2779020219 @default.
• W4366992567 cites W2784037295 @default.
• W4366992567 cites W2799524357 @default.
• W4366992567 cites W2801983997 @default.
• W4366992567 cites W2884468078 @default.
• W4366992567 cites W2899343599 @default.
• W4366992567 cites W2924139971 @default.
• W4366992567 cites W2940519434 @default.
• W4366992567 cites W2947148098 @default.
• W4366992567 cites W2950354111 @default.
• W4366992567 cites W2954682214 @default.
• W4366992567 cites W2969924257 @default.
• W4366992567 cites W2992976869 @default.
• W4366992567 cites W3002594062 @default.
• W4366992567 cites W3011497058 @default.
• W4366992567 cites W3015872136 @default.
• W4366992567 cites W3033601502 @default.
• W4366992567 cites W3043560354 @default.
• W4366992567 cites W3047667075 @default.
• W4366992567 cites W3085694914 @default.
• W4366992567 cites W3088464692 @default.
• W4366992567 cites W3091062821 @default.
• W4366992567 cites W3135339687 @default.
• W4366992567 cites W3135815505 @default.
• W4366992567 cites W3138462712 @default.
• W4366992567 cites W3158952491 @default.
• W4366992567 cites W3196504904 @default.
• W4366992567 cites W4200310435 @default.
• W4366992567 cites W4210962045 @default.
• W4366992567 cites W4280608772 @default.

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