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- W4366992870 abstract "Patient interest in non-trial access pathways to investigational cell-and gene-based interventions, such as expanded access in the USA, is increasing, while the regulatory and business environments for non-trial access in the cell and gene therapy field are shifting. Against this background, in 2022 the International Society for Cell & Gene Therapy (ISCT) established a Working Group on Expanded Access to identify practical, ethical, and regulatory issues emerging from the use (and possible misuse) of the expanded access pathway in the cell and gene therapy field. In this Short Report, the Working Group sets the stage for its future activities by analyzing the history of expanded access and identifying three examples of questions that we anticipate arising as uses of expanded access for investigational cell and gene-based interventions increase and evolve." @default.
- W4366992870 created "2023-04-27" @default.
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- W4366992870 date "2023-07-01" @default.
- W4366992870 modified "2023-09-30" @default.
- W4366992870 title "An International Society for Cell & Gene Therapy working group short report on the future of expanded access to unapproved cell and gene therapies" @default.
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- W4366992870 doi "https://doi.org/10.1016/j.jcyt.2023.02.004" @default.
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