Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366996410> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W4366996410 endingPage "221" @default.
- W4366996410 startingPage "212" @default.
- W4366996410 abstract "To explore the function of LPCAT1 in hepatocellular carcinoma progression.Bioinformatics analysis was utilized to the data from TCGA to explore the level of LPCAT1 between normal and tumor tissues, as well as the relationship between LPCAT1 level and tumor grade and prognosis of HCC. Subsequently, we used siRNA to silence LPCAT1 in HCC cells to detect cell proliferation, migration, and invasion ability.The expression of LPCAT1 was significantly increased in HCC tissues. High LPCAT1 expression was correlated with high histologic grade and poor prognosis of HCC. In addition, silencing of LPCAT1 inhibited the proliferation, migration and invasion of liver cancer cells. Moreover, LPCAT1 knockdown suppressed S100A11 and Snail both at mRNA and protein level.LPCAT1 promoted the growth, invasion and migration of HCC cells by regulating S100A11 and Snail. Therefore, LPCAT1 may serve as a potential molecular target for the diagnosis and treatment of HCC." @default.
- W4366996410 created "2023-04-27" @default.
- W4366996410 creator A5014336598 @default.
- W4366996410 creator A5027835055 @default.
- W4366996410 creator A5060379534 @default.
- W4366996410 creator A5064175547 @default.
- W4366996410 creator A5077370870 @default.
- W4366996410 date "2023-03-01" @default.
- W4366996410 modified "2023-09-30" @default.
- W4366996410 title "Knockdown of LPCAT1 Repressed Hepatocellular Carcinoma Growth and Invasion by Targeting S100A11." @default.
- W4366996410 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37094849" @default.
- W4366996410 hasPublicationYear "2023" @default.
- W4366996410 type Work @default.
- W4366996410 citedByCount "0" @default.
- W4366996410 crossrefType "journal-article" @default.
- W4366996410 hasAuthorship W4366996410A5014336598 @default.
- W4366996410 hasAuthorship W4366996410A5027835055 @default.
- W4366996410 hasAuthorship W4366996410A5060379534 @default.
- W4366996410 hasAuthorship W4366996410A5064175547 @default.
- W4366996410 hasAuthorship W4366996410A5077370870 @default.
- W4366996410 hasConcept C104317684 @default.
- W4366996410 hasConcept C119056186 @default.
- W4366996410 hasConcept C126322002 @default.
- W4366996410 hasConcept C173396325 @default.
- W4366996410 hasConcept C190283241 @default.
- W4366996410 hasConcept C2776231280 @default.
- W4366996410 hasConcept C2778019345 @default.
- W4366996410 hasConcept C502942594 @default.
- W4366996410 hasConcept C55493867 @default.
- W4366996410 hasConcept C62112901 @default.
- W4366996410 hasConcept C71924100 @default.
- W4366996410 hasConcept C86803240 @default.
- W4366996410 hasConceptScore W4366996410C104317684 @default.
- W4366996410 hasConceptScore W4366996410C119056186 @default.
- W4366996410 hasConceptScore W4366996410C126322002 @default.
- W4366996410 hasConceptScore W4366996410C173396325 @default.
- W4366996410 hasConceptScore W4366996410C190283241 @default.
- W4366996410 hasConceptScore W4366996410C2776231280 @default.
- W4366996410 hasConceptScore W4366996410C2778019345 @default.
- W4366996410 hasConceptScore W4366996410C502942594 @default.
- W4366996410 hasConceptScore W4366996410C55493867 @default.
- W4366996410 hasConceptScore W4366996410C62112901 @default.
- W4366996410 hasConceptScore W4366996410C71924100 @default.
- W4366996410 hasConceptScore W4366996410C86803240 @default.
- W4366996410 hasIssue "2" @default.
- W4366996410 hasLocation W43669964101 @default.
- W4366996410 hasOpenAccess W4366996410 @default.
- W4366996410 hasPrimaryLocation W43669964101 @default.
- W4366996410 hasRelatedWork W2039201715 @default.
- W4366996410 hasRelatedWork W2898075173 @default.
- W4366996410 hasRelatedWork W3003406165 @default.
- W4366996410 hasRelatedWork W3005549771 @default.
- W4366996410 hasRelatedWork W3095403005 @default.
- W4366996410 hasRelatedWork W3125058930 @default.
- W4366996410 hasRelatedWork W3155760817 @default.
- W4366996410 hasRelatedWork W3217378727 @default.
- W4366996410 hasRelatedWork W4297053077 @default.
- W4366996410 hasRelatedWork W4322723986 @default.
- W4366996410 hasVolume "53" @default.
- W4366996410 isParatext "false" @default.
- W4366996410 isRetracted "false" @default.
- W4366996410 workType "article" @default.