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- W4366996511 abstract "Duodenal-type follicular lymphoma (DFL) is a unique subtype of follicular lymphoma (FL), which often involves the second portion of duodenum (descending part of duodenum). Due to its specific pathological features, such as lack of follicular dendritic cells meshwork and disappearance of activation-induced cytidine deaminase expression, DFL presents an inert clinical course and is often confined to the intestinal tract. Inflammation-related biomarkers suggest that the microenvironment may play a likely role in the pathogenesis and favorable prognosis of DFL. Since patients generally have no obvious clinical symptoms and low progression rate, the treatment regimen for DFL is mainly observation and waiting (W&W) strategy. This study will review the latest research progress of epidemiology, diagnosis, treatment and prognosis of DFL in recent years.十二指肠型滤泡性淋巴瘤的临床研究进展.十二指肠型滤泡性淋巴瘤（DFL）是滤泡性淋巴瘤的一种独特亚型，常累及十二指肠第二部（降部），因其特殊的病理特征，如滤泡树突状细胞网状结构缺乏、活化诱导的胞苷脱氨酶表达消失等，呈现惰性的临床病程且病变常局限于肠道内。炎症相关标志物提示微环境可能在DFL的发病机制及其良好的预后中发挥作用。由于患者一般无明显临床症状且进展率低，故DFL的治疗方案主要为观察和等待。本文将对DFL近年来的流行病学、诊断、治疗和预后的最新研究进展作一综述。." @default.
- W4366996511 created "2023-04-27" @default.
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- W4366996511 date "2023-04-01" @default.
- W4366996511 modified "2023-09-27" @default.
- W4366996511 title "[Clinical Research Advances of Duodenal-Type Follicular Lymphoma--Review]." @default.
- W4366996511 doi "https://doi.org/10.19746/j.cnki.issn.1009-2137.2023.02.039" @default.
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