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- W4366996738 abstract "SARS-CoV-2-induced immune thrombocytopenia (SARS-CoV-2-induced ITP) is an autoimmune disease secondary to virus infections. Its diagnosis is often based on exclusion of other possible causes of thrombocytopenia in COVID-19 patients. Common laboratory examinations include coagulation function, thrombopoietin and drug-dependent antibodies. Since both bleeding and thrombosis risks are seen in SARS-CoV-2-induced ITP patients, individual remedy is essential for the treatment of this disease. Because thrombopoietin receptor agonist(TPO-RA) has the side effect of accelerating thrombosis and may aggravate the pulmonary embolism symptoms of patients, it should be used for refractory SARS-CoV-2-induced ITP patients only. This review briefly summarizes the recent research progress in the pathogenesis, diagnosis and treatment of SARS-CoV-2-induced ITP.新型冠状病毒诱导的原发免疫性血小板减少症的研究进展.新型冠状病毒诱导的原发免疫性血小板减少症（SARS-CoV-2-induced ITP）是一种继发于病毒感染的自身免疫性疾病。该病主要通过排除法诊断，需检测凝血四项、血小板生成素、药物依赖性抗体等指标，与其他导致血小板数降低的诱因鉴别后谨慎诊断。如何平衡出血与血栓风险，制定个体化给药方案是该病治疗的重点与难点。由于血小板生成素受体激动剂（TPO-RA）存在加速血栓形成的副作用，可能加重患者肺栓塞症状，因此仅用于难治性SARS-CoV-2-induced ITP患者。本文就SARS-CoV-2-induced ITP的发病机制、诊断及治疗方案的最新研究进展作一综述。." @default.
- W4366996738 created "2023-04-27" @default.
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- W4366996738 date "2023-04-01" @default.
- W4366996738 modified "2023-10-17" @default.
- W4366996738 title "[Recent Advances in SARS-CoV-2-Induced Immune Thrombocytopenia --Review]." @default.
- W4366996738 doi "https://doi.org/10.19746/j.cnki.issn.1009-2137.2023.02.042" @default.
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