FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366997612> ?p ?o ?g. }

• W4366997612 endingPage "1781" @default.
• W4366997612 startingPage "1773" @default.
• W4366997612 abstract "Abstract Background In addition to the reduction of symptomatic gallstone disease, ursodeoxycholic acid (UDCA) might also have beneficial metabolic effects after bariatric surgery. We examined the impact of UDCA on liver enzymes, hemoglobin A1c (HbA1c), lipids, and inflammation markers. Methods Patients in the UPGRADE trial (placebo-controlled, double-blind) were randomized between UDCA 900 mg daily or placebo pills for 6 months after bariatric surgery. Patients without blood measurements pre- or 6 months postoperatively were excluded. The change in liver enzymes, Hba1c, lipids, and inflammation markers after surgery were compared between the UDCA and placebo group, followed by a postoperative cross-sectional comparison. Results In total, 513 patients were included (age [mean ± SD] 45.6 ± 10.7 years; 79% female). Preoperative blood values did not differ between UDCA ( n = 266) and placebo ( n = 247) groups. Increase of alkaline phosphatase (ALP) was greater in the UDCA group (mean difference 3.81 U/l [95%CI 0.50 7.12]). Change in other liver enzymes, HbA1c, lipids, and CRP levels did not differ. Postoperative cross-sectional comparison in 316 adherent patients also revealed a higher total cholesterol (mean difference 0.25 mg/dl [95%CI 0.07–0.42]), lower aspartate aminotransferase (mean difference −3.12 U/l [−5.16 – −1.08]), and lower alanine aminotransferase level (mean difference −5.89 U/l [−9.41 – −2.37]) in the UDCA group. Conclusion UDCA treatment leads to a higher, but clinically irrelevant increase in ALP level in patients 6 months after bariatric surgery. No other changes in metabolic or inflammatory markers were observed. Except for the reduction of gallstone formation, UDCA has no effects after bariatric surgery. Graphical Abstract" @default.
• W4366997612 created "2023-04-27" @default.
• W4366997612 creator A5025198334 @default.
• W4366997612 creator A5033408512 @default.
• W4366997612 creator A5040981713 @default.
• W4366997612 creator A5049755270 @default.
• W4366997612 creator A5064653989 @default.
• W4366997612 creator A5071037040 @default.
• W4366997612 creator A5083462005 @default.
• W4366997612 date "2023-04-25" @default.
• W4366997612 modified "2023-09-26" @default.
• W4366997612 title "Ursodeoxycholic Acid Use After Bariatric Surgery: Effects on Metabolic and Inflammatory Blood Markers" @default.
• W4366997612 cites W1485743758 @default.
• W4366997612 cites W1874895607 @default.
• W4366997612 cites W1971477601 @default.
• W4366997612 cites W1981808636 @default.
• W4366997612 cites W1996486805 @default.
• W4366997612 cites W2023000637 @default.
• W4366997612 cites W2032374289 @default.
• W4366997612 cites W2072117483 @default.
• W4366997612 cites W2087228124 @default.
• W4366997612 cites W2107908836 @default.
• W4366997612 cites W2108326867 @default.
• W4366997612 cites W2144115070 @default.
• W4366997612 cites W2163508251 @default.
• W4366997612 cites W2331185476 @default.
• W4366997612 cites W2552283579 @default.
• W4366997612 cites W2588731317 @default.
• W4366997612 cites W2752460768 @default.
• W4366997612 cites W2772909894 @default.
• W4366997612 cites W2776373997 @default.
• W4366997612 cites W2901264897 @default.
• W4366997612 cites W2943036267 @default.
• W4366997612 cites W2943839145 @default.
• W4366997612 cites W2985436189 @default.
• W4366997612 cites W2991491193 @default.
• W4366997612 cites W3011953865 @default.
• W4366997612 cites W3016352931 @default.
• W4366997612 cites W3039481628 @default.
• W4366997612 cites W4213061959 @default.
• W4366997612 cites W4225910667 @default.
• W4366997612 cites W3045232978 @default.
• W4366997612 doi "https://doi.org/10.1007/s11695-023-06581-8" @default.
• W4366997612 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37186289" @default.
• W4366997612 hasPublicationYear "2023" @default.
• W4366997612 type Work @default.
• W4366997612 citedByCount "0" @default.
• W4366997612 crossrefType "journal-article" @default.
• W4366997612 hasAuthorship W4366997612A5025198334 @default.
• W4366997612 hasAuthorship W4366997612A5033408512 @default.
• W4366997612 hasAuthorship W4366997612A5040981713 @default.
• W4366997612 hasAuthorship W4366997612A5049755270 @default.
• W4366997612 hasAuthorship W4366997612A5064653989 @default.
• W4366997612 hasAuthorship W4366997612A5071037040 @default.
• W4366997612 hasAuthorship W4366997612A5083462005 @default.
• W4366997612 hasBestOaLocation W43669976121 @default.
• W4366997612 hasConcept C126322002 @default.
• W4366997612 hasConcept C139572402 @default.
• W4366997612 hasConcept C141071460 @default.
• W4366997612 hasConcept C142724271 @default.
• W4366997612 hasConcept C160160445 @default.
• W4366997612 hasConcept C181199279 @default.
• W4366997612 hasConcept C185592680 @default.
• W4366997612 hasConcept C204787440 @default.
• W4366997612 hasConcept C27081682 @default.
• W4366997612 hasConcept C2778163477 @default.
• W4366997612 hasConcept C2780965833 @default.
• W4366997612 hasConcept C55493867 @default.
• W4366997612 hasConcept C71924100 @default.
• W4366997612 hasConcept C90924648 @default.
• W4366997612 hasConceptScore W4366997612C126322002 @default.
• W4366997612 hasConceptScore W4366997612C139572402 @default.
• W4366997612 hasConceptScore W4366997612C141071460 @default.
• W4366997612 hasConceptScore W4366997612C142724271 @default.
• W4366997612 hasConceptScore W4366997612C160160445 @default.
• W4366997612 hasConceptScore W4366997612C181199279 @default.
• W4366997612 hasConceptScore W4366997612C185592680 @default.
• W4366997612 hasConceptScore W4366997612C204787440 @default.
• W4366997612 hasConceptScore W4366997612C27081682 @default.
• W4366997612 hasConceptScore W4366997612C2778163477 @default.
• W4366997612 hasConceptScore W4366997612C2780965833 @default.
• W4366997612 hasConceptScore W4366997612C55493867 @default.
• W4366997612 hasConceptScore W4366997612C71924100 @default.
• W4366997612 hasConceptScore W4366997612C90924648 @default.
• W4366997612 hasIssue "6" @default.
• W4366997612 hasLocation W43669976121 @default.
• W4366997612 hasLocation W43669976122 @default.
• W4366997612 hasLocation W43669976123 @default.
• W4366997612 hasOpenAccess W4366997612 @default.
• W4366997612 hasPrimaryLocation W43669976121 @default.
• W4366997612 hasRelatedWork W2003938723 @default.
• W4366997612 hasRelatedWork W2028963438 @default.
• W4366997612 hasRelatedWork W2047967234 @default.
• W4366997612 hasRelatedWork W2118496982 @default.
• W4366997612 hasRelatedWork W2167033828 @default.
• W4366997612 hasRelatedWork W2439875401 @default.
• W4366997612 hasRelatedWork W4230813607 @default.
• W4366997612 hasRelatedWork W4238867864 @default.

• next