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- W4366998868 abstract "Bacteria must synthesize their cell wall and membrane during their cell cycle, with peptidoglycan being the primary component of the cell wall in most bacteria. Peptidoglycan is a three-dimensional polymer that enables bacteria to resist cytoplasmic osmotic pressure, maintain their cell shape and protect themselves from environmental threats. Numerous antibiotics that are currently used target enzymes involved in the synthesis of the cell wall, particularly peptidoglycan synthases. In this review, we highlight recent progress in our understanding of peptidoglycan synthesis, remodeling, repair, and regulation in two model bacteria: the Gram-negative Escherichia coli and the Gram-positive Bacillus subtilis. By summarizing the latest findings in this field, we hope to provide a comprehensive overview of peptidoglycan biology, which is critical for our understanding of bacterial adaptation and antibiotic resistance." @default.
- W4366998868 created "2023-04-27" @default.
- W4366998868 creator A5013711709 @default.
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- W4366998868 creator A5052837496 @default.
- W4366998868 creator A5078718223 @default.
- W4366998868 creator A5089764437 @default.
- W4366998868 date "2023-04-22" @default.
- W4366998868 modified "2023-10-17" @default.
- W4366998868 title "Recent Advances in Peptidoglycan Synthesis and Regulation in Bacteria" @default.
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