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- W4367016726 abstract "Aldo-keto reductase family 1C (AKR1C) members transform steroids via their 3-, 17-, and 20-ketosteroid reductase activities. The biochemical study of these enzymes can help to inform their roles in hormone-dependent diseases and develop therapeutic inhibitors. This work describes a protocol to purify AKR1C1-4 members from a bacterial expression system using two chromatography steps. It also describes the basis of discontinuous assays to measure steroid conversion." @default.
- W4367016726 created "2023-04-27" @default.
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- W4367016726 date "2023-01-01" @default.
- W4367016726 modified "2023-10-14" @default.
- W4367016726 title "Aldo keto-reductase family 1C members 1 through 4 recombinant enzyme purification and enzyme assay" @default.
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- W4367016726 doi "https://doi.org/10.1016/bs.mie.2023.04.007" @default.
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