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- W4367017572 abstract "A new method detects single molecules using a chemical reaction and creates images with high sensitivity and high spatial resolution such as those made with superresolution microscopy. Superresolution microscopy creates images of surfaces by detecting individual molecules, but it is done with fluorescence and requires the use of lasers, which can damage some samples and bleach the fluorescent labels. Jiandong Feng and coworkers at Zhejiang University have imaged individual electrochemical reactions using electrochemiluminescence (ECL), in which an applied voltage drives light-emitting reactions ( Nature 2021, DOI: 10.1038/s41586-021-03715-9 ). ECL “does not require the use of excitation light, which is a benefit to achieve very low background and ultrahigh sensitivity for resolving weak signals,” Feng says. The researchers used a well-studied ECL reaction between tris(2,2′-bipyridyl)ruthenium(II), also called Ru(bpy) 3 2+ , and tri- n -propylamine (TPrA). In this system, an applied voltage oxidizes the Ru complex at the surface of an" @default.
- W4367017572 created "2023-04-27" @default.
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- W4367017572 date "2021-08-23" @default.
- W4367017572 modified "2023-09-23" @default.
- W4367017572 title "Electrochemical method allows imaging of single reactions" @default.
- W4367017572 doi "https://doi.org/10.1021/cen-09930-scicon6" @default.
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