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- W4367031348 abstract "Carbon quantum dots (CQDs) have a size of 10 nm (or less), with lots of biomedical advantages, creating huge excitement in different research fields. The aim of this study includes an eco-friendly synthesis of biogenic CQDs from grape (<i>Vitis vinifera</i>) seeds, identifying the characteristics and assessing its anti-diabetic as well as anti-microbial activity. CQDs are prepared by the pyrolysis method. Synthesized CQDs were confirmed by ultraviolet (UV)–visible (Vis) spectrophotometer, and the characterization study was done by X-ray diffractometer, photoluminescence spectroscopy, Fourier transform infra-red spectroscopy, and transmission electron microscopy with selected area electron diffraction (SAED). Anti-diabetic activity of CQDs was analyzed by <i>in vitro</i> α-glycosidase, α-amylase inhibition assays, and glucose uptake studies. The anti-bacterial activity of CQDs was analyzed by anti-microbial assay technique against <i>Escherichia coli, Pseudomonas aeruginosa</i>, <i>Staphylococcus aureus,</i> and <i>Streptococcus mutans</i>. The results showed that the CQDs synthesized from a natural source like grape seeds, were amorphous in nature, the average particle size was 4 nm, and they contain functional groups like carboxyl and hydroxyl. Subsequently, it showed that the sp2 domains also produce green fluorescence. The anti-diabetic experimental method revealed that the CQDs enhance glucose uptake and inhibit carbohydrate hydrolyzing enzymes. CQDs also exhibit anti-bacterial properties against both Gram-positive and Gram-negative bacteria, according to their antimicrobial impact. Due to their small size and higher activity, CQDs will become strong anti-diabetic agents as well as anti-bacterial ones." @default.
- W4367031348 created "2023-04-27" @default.
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- W4367031348 date "2023-03-01" @default.
- W4367031348 modified "2023-10-14" @default.
- W4367031348 title "Evaluation of Anti-diabetic Potential of Anti-microbial Carbon Quantum Dots from <i>Vitis vinifera</i> Seeds" @default.
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- W4367031348 doi "https://doi.org/10.26599/nbe.2023.9290002" @default.
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