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- W4367046967 abstract "Nature-inspired nanostructured surfaces with intrinsic mechano-bactericidal behaviors have drawn particular attention, owing to the advantages of biocompatibility, no cytotoxicity and free of biocides. However, when encountered with different bacterial strains, those nanostructured surfaces show significant different antibacterial activities because of the obvious variability in bacterial cell wall and morphology. Herein, a mechano-bactericidal nanostructured surface with photothermally enhanced antibacterial performances has been developed, which exhibits synergistic antimicrobial performances with significantly enhanced antibacterial efficiency against both Gram-positive and Gram-negative bacteria. Firstly, a nanopillar surface with mechano-bactericidal properties is replicated by AAO template methods. Afterwards, a thin photothermal layer of polydopamine (PDA) was rapidly deposited on the nanostructured surface. The resultant nanopillar surface displays remarkably high antibacterial activities against both Gram-positive Staphylococcus aureus (S. aureus) and Gram-negative Escherichia coli (E. coli). The main reason is due to the photothermal (PTT) effect from the NIR irradiated PDA layer makes the bacterial cell membranes more susceptible to be killed by the structural rupture of the nanopillar surface. Additionally, the nanopillar surface also exhibited excellent hemocompatibility and cytocompatibility properties. Benefiting from the obviously enhanced mechano-bactericidal performances with no antibacterial agents involved, our study might display promising potentials in broad antibacterial applications, ranging from healthcare settings, biomedical ingredients, and other high risk instruments." @default.
- W4367046967 created "2023-04-27" @default.
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- W4367046967 date "2023-09-01" @default.
- W4367046967 modified "2023-10-16" @default.
- W4367046967 title "Nature-inspired mechano-bactericidal nanostructured surfaces with photothermally enhanced antibacterial performances" @default.
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- W4367046967 doi "https://doi.org/10.1016/j.porgcoat.2023.107599" @default.
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