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• W4367048105 abstract "Signal peptidase I is an important drug target, and understanding its substrate is critically important to develop new bacterium-specific drugs. To that end, we have a unique signal peptide that we have shown is refractory to processing by LepB, the essential signal peptidase I in E. coli , but previously has been shown to be processed by a more human-like signal peptidase found in some bacteria." @default.
• W4367048105 created "2023-04-27" @default.
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• W4367048105 date "2023-06-15" @default.
• W4367048105 modified "2023-10-18" @default.
• W4367048105 title "New Perspectives on Escherichia coli Signal Peptidase I Substrate Specificity: Investigating Why the TasA Cleavage Site Is Incompatible with LepB Cleavage" @default.
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• W4367048105 doi "https://doi.org/10.1128/spectrum.05005-22" @default.
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