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- W4367052904 abstract "The factors influencing the appearance of toxicity in samples of synthetic montmorillonite with a systematically changing chemical composition Nax(Al, Mg)2-3Si4O10(OH)2 nH2O, which are potentially important for their use in medicine as drug carriers, targeted drug delivery systems, entero- and hemosorbents have been studied. Samples synthesized under hydrothermal conditions had the morphology of nanolayers self-organized into the nanosponge structures. The effect of the aluminum content, particle sizes, porosity, and ζ-potential of the samples on their toxicity was studied. The cytotoxic effect of the samples on eukaryotic cells Ea. hy 926 was determined using the MTT assay. The hemolytic activity of the samples in the wide concentration range in relation to human erythrocytes was also estimated. It has been established that the toxicity of aluminosilicate nanoparticles can be significantly reduced by correctly selecting their synthesis conditions and chemical composition, which opens up the opportunities for their use in medicine." @default.
- W4367052904 created "2023-04-27" @default.
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- W4367052904 date "2023-04-25" @default.
- W4367052904 modified "2023-10-18" @default.
- W4367052904 title "Hemolytic Activity and Cytotoxicity of Synthetic Nanoclays with Montmorillonite Structure for Medical Applications" @default.
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- W4367052904 doi "https://doi.org/10.3390/nano13091470" @default.
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