FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4367173652> ?p ?o ?g. }

• W4367173652 endingPage "1106" @default.
• W4367173652 startingPage "1104" @default.
• W4367173652 abstract "HomeCirculation ResearchVol. 132, No. 9Targeting Small-Conductance Calcium-Activated Potassium Channels in Atrial Fibrillation: Therapeutic Opportunities No AccessEditorialRequest AccessFull TextAboutView Full TextView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toNo AccessEditorialRequest AccessFull TextTargeting Small-Conductance Calcium-Activated Potassium Channels in Atrial Fibrillation: Therapeutic Opportunities Xiao-Dong Zhang and Nipavan Chiamvimonvat Xiao-Dong ZhangXiao-Dong Zhang https://orcid.org/0000-0002-1042-8823 Division of Cardiovascular Medicine, Department of Internal Medicine (X.-D.Z., N.C.), School of Medicine, University of California, Davis. Search for more papers by this author and Nipavan ChiamvimonvatNipavan Chiamvimonvat Correspondence to: Nipavan Chiamvimonvat, MD, University of California, Davis, 451 Health Science Dr, GBSF 6315, Davis, CA 95616. Email E-mail Address: [email protected] https://orcid.org/0000-0001-9499-8817 Division of Cardiovascular Medicine, Department of Internal Medicine (X.-D.Z., N.C.), School of Medicine, University of California, Davis. Department of Pharmacology (N.C.), School of Medicine, University of California, Davis. Department of Veterans Affairs, Northern California Health Care System, Mather (N.C.). Search for more papers by this author Originally published27 Apr 2023https://doi.org/10.1161/CIRCRESAHA.123.322777Circulation Research. 2023;132:1104–1106This article is a commentary on the followingEnhanced Ca2+-Dependent SK-Channel Gating and Membrane Trafficking in Human Atrial FibrillationFootnotesFor Sources of Funding and Disclosures, see page 1106.The opinions expressed in this article are not necessarily those of the editors or of the American Heart Association.Correspondence to: Nipavan Chiamvimonvat, MD, University of California, Davis, 451 Health Science Dr, GBSF 6315, Davis, CA 95616. Email [email protected].eduReferences1. Xu Y, Tuteja D, Zhang Z, Xu D, Zhang Y, Rodriguez J, Nie L, Tuxson HR, Young JN, Glatter KA, et al. Molecular identification and functional roles of a Ca2+-activated K+ channel in human and mouse hearts.J Biol Chem. 2003; 278:49085–49094. doi: 10.1074/jbc.M307508200CrossrefMedlineGoogle Scholar2. Zhang Q, Timofeyev V, Lu L, Li N, Singapuri A, Long MK, Bond CT, Adelman JP, Chiamvimonvat N. Functional roles of a Ca2+-activated K+ channel in atrioventricular nodes.Circ Res. 2008; 102:465–471. doi: 10.1161/CIRCRESAHA.107.161778LinkGoogle Scholar3. Torrente AG, Zhang R, Wang H, Zaini A, Kim B, Yue X, Philipson KD, Goldhaber JI. Contribution of small conductance K+ channels to sinoatrial node pacemaker activity: insights from atrial-specific Na+/Ca2+ exchange knockout mice.J Physiol. 2017; 595:3847–3865. doi: 10.1113/JP274249CrossrefMedlineGoogle Scholar4. Zhang XD, Lieu DK, Chiamvimonvat N. Small-conductance Ca2+-activated K+ channels and cardiac arrhythmias.Heart Rhythm. 2015; 12:1845–1851. doi: 10.1016/j.hrthm.2015.04.046CrossrefMedlineGoogle Scholar5. Zhang XD, Thai PN, Lieu DK, Chiamvimonvat N. Cardiac small-conductance calcium-activated potassium channels in health and disease.Pflugers Arch. 2021; 473:477–489. doi: 10.1007/s00424-021-02535-0CrossrefMedlineGoogle Scholar6. Chang PC, Chen PS. SK channels and ventricular arrhythmias in heart failure.Trends Cardiovasc Med. 2015; 25:508–514. doi: 10.1016/j.tcm.2015.01.010CrossrefMedlineGoogle Scholar7. Gal P, Klaassen ES, Bergmann KR, Saghari M, Burggraaf J, Kemme MJB, Sylvest C, Sorensen U, Bentzen BH, Grunnet M, et al. First clinical study with ap30663 - a KCa 2 channel inhibitor in development for conversion of atrial fibrillation.Clin Transl Sci. 2020; 13:1336–1344. doi: 10.1111/cts.12835CrossrefMedlineGoogle Scholar8. Darkow E, Nguyen TT, Stolina M, Kari FA, Schmidt C, Wiedmann F, Baczko I, Kohl P, Rajamani S, Ravens U, et al. Small conductance Ca2+-activated K+ (SK) channel mrna expression in human atrial and ventricular tissue: comparison between donor, atrial fibrillation and heart failure tissue.Front Physiol. 2021; 12:650964. doi: 10.3389/fphys.2021.650964CrossrefMedlineGoogle Scholar9. Yu T, Deng C, Wu R, Guo H, Zheng S, Yu X, Shan Z, Kuang S, Lin Q. Decreased expression of small-conductance Ca2+-activated K+ channels SK1 and Sk2 in human chronic atrial fibrillation.Life Sci. 2012; 90:219–227. doi: 10.1016/j.lfs.2011.11.008CrossrefMedlineGoogle Scholar10. Heijman J, Zhou X, Morotti S, Molina CE, Abu-Taha IH, Tekook M, Jespersen T, Zhang Y, Dobrev S, Milting H, et al. Enhanced Ca2+-dependent SK-channel gating and membrane trafficking in human atrial fibrillation.Circ Res. 2023; 132:e116–e133. doi: 10.1161/CIRCRESAHA.122.321858LinkGoogle Scholar11. Lu L, Timofeyev V, Li N, Rafizadeh S, Singapuri A, Harris TR, Chiamvimonvat N. Alpha-actinin2 cytoskeletal protein is required for the functional membrane localization of a Ca2+-activated K+ channel (SK2 channel).Proc Natl Acad Sci USA. 2009; 106:18402–18407. doi: 10.1073/pnas.0908207106CrossrefMedlineGoogle Scholar12. Zhang XD, Coulibaly ZA, Chen WC, Ledford HA, Lee JH, Sirish P, Dai G, Jian Z, Chuang F, Brust-Mascher I, et al. Coupling of SK channels, L-type Ca2+ channels, and ryanodine receptors in cardiomyocytes.Sci Rep. 2018; 8:4670. doi: 10.1038/s41598-018-22843-3CrossrefMedlineGoogle Scholar13. Lee CH, MacKinnon R. Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures.Science. 2018; 360:508–513. doi: 10.1126/science.aas9466CrossrefMedlineGoogle Scholar14. Jumper J, Evans R, Pritzel A, Green T, Figurnov M, Ronneberger O, Tunyasuvunakool K, Bates R, Zidek A, Potapenko A, et al. Highly accurate protein structure prediction with alphafold.Nature. 2021; 596:583–589. doi: 10.1038/s41586-021-03819-2CrossrefMedlineGoogle Scholar15. Kim TY, Terentyeva R, Roder KH, Li W, Liu M, Greener I, Hamilton S, Polina I, Murphy KR, Clements RT, et al. SK channel enhancers attenuate Ca2+-dependent arrhythmia in hypertrophic hearts by regulating mito-ROS-dependent oxidation and activity of ryr.Cardiovasc Res. 2017; 113:343–353. doi: 10.1093/cvr/cvx005CrossrefMedlineGoogle Scholar eLetters(0)eLetters should relate to an article recently published in the journal and are not a forum for providing unpublished data. Comments are reviewed for appropriate use of tone and language. Comments are not peer-reviewed. Acceptable comments are posted to the journal website only. Comments are not published in an issue and are not indexed in PubMed. Comments should be no longer than 500 words and will only be posted online. References are limited to 10. Authors of the article cited in the comment will be invited to reply, as appropriate.Comments and feedback on AHA/ASA Scientific Statements and Guidelines should be directed to the AHA/ASA Manuscript Oversight Committee via its Correspondence page.Sign In to Submit a Response to This Article Previous Back to top Next FiguresReferencesRelatedDetailsRelated articlesEnhanced Ca2+-Dependent SK-Channel Gating and Membrane Trafficking in Human Atrial FibrillationJordi Heijman, et al. Circulation Research. 2023;132:e116-e133 April 28, 2023Vol 132, Issue 9 Advertisement Article InformationMetrics © 2023 American Heart Association, Inc.https://doi.org/10.1161/CIRCRESAHA.123.322777PMID: 37104564 Originally publishedApril 27, 2023 Keywordsheartatrial fibrillationsmall-conductance calcium-activated potassium channelsEditorialhumansPDF download Advertisement" @default.
• W4367173652 created "2023-04-28" @default.
• W4367173652 creator A5031817215 @default.
• W4367173652 creator A5051855892 @default.
• W4367173652 date "2023-04-28" @default.
• W4367173652 modified "2023-09-23" @default.
• W4367173652 title "Targeting Small-Conductance Calcium-Activated Potassium Channels in Atrial Fibrillation: Therapeutic Opportunities" @default.
• W4367173652 cites W1997925229 @default.
• W4367173652 cites W2021566149 @default.
• W4367173652 cites W2040437516 @default.
• W4367173652 cites W2081096698 @default.
• W4367173652 cites W2134183956 @default.
• W4367173652 cites W2161163873 @default.
• W4367173652 cites W2573826438 @default.
• W4367173652 cites W2599407056 @default.
• W4367173652 cites W2801595722 @default.
• W4367173652 cites W2806466730 @default.
• W4367173652 cites W3045689726 @default.
• W4367173652 cites W3131541529 @default.
• W4367173652 cites W3142706615 @default.
• W4367173652 cites W3177828909 @default.
• W4367173652 cites W4327678290 @default.
• W4367173652 doi "https://doi.org/10.1161/circresaha.123.322777" @default.
• W4367173652 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37104564" @default.
• W4367173652 hasPublicationYear "2023" @default.
• W4367173652 type Work @default.
• W4367173652 citedByCount "0" @default.
• W4367173652 crossrefType "journal-article" @default.
• W4367173652 hasAuthorship W4367173652A5031817215 @default.
• W4367173652 hasAuthorship W4367173652A5051855892 @default.
• W4367173652 hasConcept C126322002 @default.
• W4367173652 hasConcept C149614440 @default.
• W4367173652 hasConcept C164705383 @default.
• W4367173652 hasConcept C2779161974 @default.
• W4367173652 hasConcept C2780971015 @default.
• W4367173652 hasConcept C512399662 @default.
• W4367173652 hasConcept C71924100 @default.
• W4367173652 hasConcept C83743174 @default.
• W4367173652 hasConceptScore W4367173652C126322002 @default.
• W4367173652 hasConceptScore W4367173652C149614440 @default.
• W4367173652 hasConceptScore W4367173652C164705383 @default.
• W4367173652 hasConceptScore W4367173652C2779161974 @default.
• W4367173652 hasConceptScore W4367173652C2780971015 @default.
• W4367173652 hasConceptScore W4367173652C512399662 @default.
• W4367173652 hasConceptScore W4367173652C71924100 @default.
• W4367173652 hasConceptScore W4367173652C83743174 @default.
• W4367173652 hasIssue "9" @default.
• W4367173652 hasLocation W43671736521 @default.
• W4367173652 hasLocation W43671736522 @default.
• W4367173652 hasOpenAccess W4367173652 @default.
• W4367173652 hasPrimaryLocation W43671736521 @default.
• W4367173652 hasRelatedWork W1967841144 @default.
• W4367173652 hasRelatedWork W2018480046 @default.
• W4367173652 hasRelatedWork W2064495796 @default.
• W4367173652 hasRelatedWork W2319489406 @default.
• W4367173652 hasRelatedWork W2333279585 @default.
• W4367173652 hasRelatedWork W2603808924 @default.
• W4367173652 hasRelatedWork W2763816051 @default.
• W4367173652 hasRelatedWork W2793053827 @default.
• W4367173652 hasRelatedWork W2889073610 @default.
• W4367173652 hasRelatedWork W3132289493 @default.
• W4367173652 hasVolume "132" @default.
• W4367173652 isParatext "false" @default.
• W4367173652 isRetracted "false" @default.
• W4367173652 workType "article" @default.