Matches in SemOpenAlex for { <https://semopenalex.org/work/W4367174958> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W4367174958 endingPage "1768" @default.
- W4367174958 startingPage "1762" @default.
- W4367174958 abstract "Patients with sickle cell disease (SCD) are predisposed to a hypercoagulable state. Despite the increased risk of venous thromboembolism in the SCD population, there is limited evidence available to guide thromboprophylaxis (TP) practices in these patients. This study aimed to assess the use of pharmacologic and nonpharmacologic TP in adolescent patients with SCD using the Pediatric Health Information System (PHIS). We hypothesized that TP was increasingly used in hospitalized adolescent patients with SCD. The study included patients with SCD aged 13 to 21 years, admitted to a PHIS hospital between 1 January, 2010, and 30 June, 2021. A total of 7202 unique patients consisting of 34 094 unique admissions were included for analyses. Pharmacologic or mechanical TP was used in 2600 (7.6%) admissions, with 3.6% of admissions (n = 1225) receiving pharmacologic prophylaxis and 4.3% (n = 1474) receiving mechanical prophylaxis. Pharmacologic TP increased in use from 1.3% of admissions in 2010 to 14.4% in the first half of 2021. Enoxaparin was the most commonly prescribed anticoagulant, used in 87% of admissions in which pharmacologic TP was used. The use of prophylactic direct oral anticoagulants was first documented in 2018 and increased to 25% of admissions with pharmacologic TP by 2021. This study demonstrates a steady increase in TP use in adolescent patients with SCD admitted to the hospital. Prospective cohort studies are needed to determine VTE risk factors in adolescents and children with SCD and the efficacy and safety of prophylactic regimens." @default.
- W4367174958 created "2023-04-28" @default.
- W4367174958 creator A5027676114 @default.
- W4367174958 creator A5050829820 @default.
- W4367174958 creator A5088652235 @default.
- W4367174958 date "2023-04-27" @default.
- W4367174958 modified "2023-10-14" @default.
- W4367174958 title "Venous thromboembolism prophylaxis in sickle cell disease: a multicenter cohort study of adolescent inpatients" @default.
- W4367174958 cites W1528211603 @default.
- W4367174958 cites W1981361161 @default.
- W4367174958 cites W1982958883 @default.
- W4367174958 cites W1983417355 @default.
- W4367174958 cites W1989546461 @default.
- W4367174958 cites W1993622417 @default.
- W4367174958 cites W2002038526 @default.
- W4367174958 cites W2016226738 @default.
- W4367174958 cites W2036595099 @default.
- W4367174958 cites W2058188211 @default.
- W4367174958 cites W2063218351 @default.
- W4367174958 cites W2073806240 @default.
- W4367174958 cites W2083687462 @default.
- W4367174958 cites W2119580559 @default.
- W4367174958 cites W2551990299 @default.
- W4367174958 cites W2560084581 @default.
- W4367174958 cites W2759478227 @default.
- W4367174958 cites W2791297643 @default.
- W4367174958 cites W2792702643 @default.
- W4367174958 cites W2797001717 @default.
- W4367174958 cites W2902174064 @default.
- W4367174958 cites W2945451030 @default.
- W4367174958 cites W2984750677 @default.
- W4367174958 cites W3029923949 @default.
- W4367174958 cites W3036739471 @default.
- W4367174958 cites W3080803704 @default.
- W4367174958 cites W3085781311 @default.
- W4367174958 cites W3096575620 @default.
- W4367174958 cites W3211260362 @default.
- W4367174958 cites W4213038960 @default.
- W4367174958 cites W4226025346 @default.
- W4367174958 cites W2914394330 @default.
- W4367174958 doi "https://doi.org/10.1182/bloodadvances.2022007802" @default.
- W4367174958 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37103974" @default.
- W4367174958 hasPublicationYear "2023" @default.
- W4367174958 type Work @default.
- W4367174958 citedByCount "1" @default.
- W4367174958 countsByYear W43671749582023 @default.
- W4367174958 crossrefType "journal-article" @default.
- W4367174958 hasAuthorship W4367174958A5027676114 @default.
- W4367174958 hasAuthorship W4367174958A5050829820 @default.
- W4367174958 hasAuthorship W4367174958A5088652235 @default.
- W4367174958 hasBestOaLocation W43671749581 @default.
- W4367174958 hasConcept C126322002 @default.
- W4367174958 hasConcept C187212893 @default.
- W4367174958 hasConcept C188816634 @default.
- W4367174958 hasConcept C201903717 @default.
- W4367174958 hasConcept C2778620579 @default.
- W4367174958 hasConcept C2779134260 @default.
- W4367174958 hasConcept C2780868729 @default.
- W4367174958 hasConcept C2780976302 @default.
- W4367174958 hasConcept C2908647359 @default.
- W4367174958 hasConcept C2991741193 @default.
- W4367174958 hasConcept C71924100 @default.
- W4367174958 hasConcept C72563966 @default.
- W4367174958 hasConcept C99454951 @default.
- W4367174958 hasConceptScore W4367174958C126322002 @default.
- W4367174958 hasConceptScore W4367174958C187212893 @default.
- W4367174958 hasConceptScore W4367174958C188816634 @default.
- W4367174958 hasConceptScore W4367174958C201903717 @default.
- W4367174958 hasConceptScore W4367174958C2778620579 @default.
- W4367174958 hasConceptScore W4367174958C2779134260 @default.
- W4367174958 hasConceptScore W4367174958C2780868729 @default.
- W4367174958 hasConceptScore W4367174958C2780976302 @default.
- W4367174958 hasConceptScore W4367174958C2908647359 @default.
- W4367174958 hasConceptScore W4367174958C2991741193 @default.
- W4367174958 hasConceptScore W4367174958C71924100 @default.
- W4367174958 hasConceptScore W4367174958C72563966 @default.
- W4367174958 hasConceptScore W4367174958C99454951 @default.
- W4367174958 hasIssue "9" @default.
- W4367174958 hasLocation W43671749581 @default.
- W4367174958 hasLocation W43671749582 @default.
- W4367174958 hasOpenAccess W4367174958 @default.
- W4367174958 hasPrimaryLocation W43671749581 @default.
- W4367174958 hasRelatedWork W2042664817 @default.
- W4367174958 hasRelatedWork W2051711579 @default.
- W4367174958 hasRelatedWork W2412545272 @default.
- W4367174958 hasRelatedWork W242090125 @default.
- W4367174958 hasRelatedWork W2539600999 @default.
- W4367174958 hasRelatedWork W2588514944 @default.
- W4367174958 hasRelatedWork W2754302395 @default.
- W4367174958 hasRelatedWork W2901334784 @default.
- W4367174958 hasRelatedWork W3214088720 @default.
- W4367174958 hasRelatedWork W4252966358 @default.
- W4367174958 hasVolume "7" @default.
- W4367174958 isParatext "false" @default.
- W4367174958 isRetracted "false" @default.
- W4367174958 workType "article" @default.