Matches in SemOpenAlex for { <https://semopenalex.org/work/W4367176189> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W4367176189 abstract "Abstract Purpose : To compare the safety and efficacy of subconjunctival injection of Mitomycin C(MMC) with sponge-applied MMC during trabeculectomy. Method s: This prospective, randomized, interventional study was conducted on consecutive patients with uncontrolled glaucoma. 137 patients were randomized into an Injection group(Group 1,n=66) and a sponge group(Group 2,n=71). Trabeculectomy was performed in all patients who were followed up on days 1, 15, 30, 3 months,6 months,1 year,2 years & 3 years postoperatively. Baseline & follow-up visits were compared to find out difference in the number of antiglaucoma medications (AGM ), Intraocular pressure(IOP), and Best Corrected Visual Acuity(BCVA).In Group 1, the surgeon used MMC 0.2 mg/ml as subconjunctival injection and two separate semicircular surgical sponges soaked with MMC solution of 0.2 mg/mL were inserted subconjunctivally in Group 2. Results :Mean preop IOP was 34.21±13.3mmHg& 34.17±10.6mmHg in group 1&2 respectively,which reduced to 11.34±3.7& 12.57±4.7mmHg(6 months),11.97±4.2& 13.60 ±5.3mmHg(1year),12.42±4.4& 11.77±2.8 mmHg(2years)&11.25±3.2&11.81±3.2mmHg at final visit(P<0.001 in both groups)with no significant difference between the groups.The mean number of preoperative AGM was 2.32±0.7&2.32±0.8 in group1&2 respectively which reduced to 0.78±0.9(P<0.001)&1.13±1.1(P=0.930)at 3 years.Overall success rates were 75.3% in group 1 and 70.7% in group 2 at 3 years(p=0.512). Postoperative complications and the final post-operative visual outcomes were similar between the groups. Conclusion : Subconjunctival Injection of MMC is as safe and effective as sponge application with comparable surgical outcomes and complications in the long term." @default.
- W4367176189 created "2023-04-28" @default.
- W4367176189 creator A5033682368 @default.
- W4367176189 creator A5040184817 @default.
- W4367176189 creator A5057001109 @default.
- W4367176189 creator A5063082995 @default.
- W4367176189 creator A5072719048 @default.
- W4367176189 creator A5091379229 @default.
- W4367176189 date "2023-04-27" @default.
- W4367176189 modified "2023-10-15" @default.
- W4367176189 title "Long-term Outcomes Of Mitomycin-C Augmented Trabeculectomy using Subconjunctival Injections Versus Soaked Sponges: A Randomized Controlled Trial" @default.
- W4367176189 cites W1999564530 @default.
- W4367176189 cites W2006693614 @default.
- W4367176189 cites W2016672745 @default.
- W4367176189 cites W2039678887 @default.
- W4367176189 cites W2042370894 @default.
- W4367176189 cites W2164183056 @default.
- W4367176189 cites W2173482566 @default.
- W4367176189 cites W2574316386 @default.
- W4367176189 cites W2588516758 @default.
- W4367176189 cites W2849598637 @default.
- W4367176189 cites W2973419879 @default.
- W4367176189 cites W2976315954 @default.
- W4367176189 cites W3012138981 @default.
- W4367176189 cites W3012550590 @default.
- W4367176189 cites W3094413856 @default.
- W4367176189 cites W3164007776 @default.
- W4367176189 cites W3209449815 @default.
- W4367176189 cites W4226150005 @default.
- W4367176189 cites W4230446976 @default.
- W4367176189 cites W4247390435 @default.
- W4367176189 cites W4249585749 @default.
- W4367176189 doi "https://doi.org/10.21203/rs.3.rs-2742647/v1" @default.
- W4367176189 hasPublicationYear "2023" @default.
- W4367176189 type Work @default.
- W4367176189 citedByCount "0" @default.
- W4367176189 crossrefType "posted-content" @default.
- W4367176189 hasAuthorship W4367176189A5033682368 @default.
- W4367176189 hasAuthorship W4367176189A5040184817 @default.
- W4367176189 hasAuthorship W4367176189A5057001109 @default.
- W4367176189 hasAuthorship W4367176189A5063082995 @default.
- W4367176189 hasAuthorship W4367176189A5072719048 @default.
- W4367176189 hasAuthorship W4367176189A5091379229 @default.
- W4367176189 hasBestOaLocation W43671761891 @default.
- W4367176189 hasConcept C118487528 @default.
- W4367176189 hasConcept C141071460 @default.
- W4367176189 hasConcept C168563851 @default.
- W4367176189 hasConcept C2777824320 @default.
- W4367176189 hasConcept C2778257484 @default.
- W4367176189 hasConcept C2778527774 @default.
- W4367176189 hasConcept C2779338040 @default.
- W4367176189 hasConcept C2781092963 @default.
- W4367176189 hasConcept C42219234 @default.
- W4367176189 hasConcept C71924100 @default.
- W4367176189 hasConceptScore W4367176189C118487528 @default.
- W4367176189 hasConceptScore W4367176189C141071460 @default.
- W4367176189 hasConceptScore W4367176189C168563851 @default.
- W4367176189 hasConceptScore W4367176189C2777824320 @default.
- W4367176189 hasConceptScore W4367176189C2778257484 @default.
- W4367176189 hasConceptScore W4367176189C2778527774 @default.
- W4367176189 hasConceptScore W4367176189C2779338040 @default.
- W4367176189 hasConceptScore W4367176189C2781092963 @default.
- W4367176189 hasConceptScore W4367176189C42219234 @default.
- W4367176189 hasConceptScore W4367176189C71924100 @default.
- W4367176189 hasLocation W43671761891 @default.
- W4367176189 hasOpenAccess W4367176189 @default.
- W4367176189 hasPrimaryLocation W43671761891 @default.
- W4367176189 hasRelatedWork W1986673086 @default.
- W4367176189 hasRelatedWork W1988712767 @default.
- W4367176189 hasRelatedWork W2022049485 @default.
- W4367176189 hasRelatedWork W2027135696 @default.
- W4367176189 hasRelatedWork W2029120146 @default.
- W4367176189 hasRelatedWork W2087068028 @default.
- W4367176189 hasRelatedWork W2349295446 @default.
- W4367176189 hasRelatedWork W2375444211 @default.
- W4367176189 hasRelatedWork W2925941772 @default.
- W4367176189 hasRelatedWork W4318211211 @default.
- W4367176189 isParatext "false" @default.
- W4367176189 isRetracted "false" @default.
- W4367176189 workType "article" @default.