FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4367182314> ?p ?o ?g. }

• W4367182314 endingPage "2503" @default.
• W4367182314 startingPage "2503" @default.
• W4367182314 abstract "The preoperative grading of non-enhancing glioma (NEG) remains challenging. Herein, we analyzed clinical and magnetic resonance imaging (MRI) features to predict malignancy in NEG according to the 2021 WHO classification and developed a clinical score, facilitating risk estimation. A discovery cohort (2012-2017, n = 72) was analyzed for MRI and clinical features (T2/FLAIR mismatch sign, subventricular zone (SVZ) involvement, tumor volume, growth rate, age, Pignatti score, and symptoms). Despite a low-grade appearance on MRI, 81% of patients were classified as WHO grade 3 or 4. Malignancy was then stratified by: (1) WHO grade (WHO grade 2 vs. WHO grade 3 + 4) and (2) molecular criteria (IDHmut WHO grade 2 + 3 vs. IDHwt glioblastoma + IDHmut astrocytoma WHO grade 4). Age, Pignatti score, SVZ involvement, and T2/FLAIR mismatch sign predicted malignancy only when considering molecular criteria, including IDH mutation and CDKN2A/B deletion status. A multivariate regression confirmed age and T2/FLAIR mismatch sign as independent predictors (p = 0.0009; p = 0.011). A risk estimation in non-enhancing glioma (RENEG) score was derived and tested in a validation cohort (2018-2019, n = 40), yielding a higher predictive value than the Pignatti score or the T2/FLAIR mismatch sign (AUC of receiver operating characteristics = 0.89). The prevalence of malignant glioma was high in this series of NEGs, supporting an upfront diagnosis and treatment approach. A clinical score with robust test performance was developed that identifies patients at risk for malignancy." @default.
• W4367182314 created "2023-04-28" @default.
• W4367182314 creator A5007118974 @default.
• W4367182314 creator A5014073957 @default.
• W4367182314 creator A5015109594 @default.
• W4367182314 creator A5019526237 @default.
• W4367182314 creator A5025477516 @default.
• W4367182314 creator A5052657395 @default.
• W4367182314 creator A5056148870 @default.
• W4367182314 creator A5079589784 @default.
• W4367182314 creator A5080916428 @default.
• W4367182314 date "2023-04-27" @default.
• W4367182314 modified "2023-09-28" @default.
• W4367182314 title "Risk Estimation in Non-Enhancing Glioma: Introducing a Clinical Score" @default.
• W4367182314 cites W1682346320 @default.
• W4367182314 cites W1812256879 @default.
• W4367182314 cites W1893588436 @default.
• W4367182314 cites W1993482432 @default.
• W4367182314 cites W1996908572 @default.
• W4367182314 cites W2002291505 @default.
• W4367182314 cites W2017129288 @default.
• W4367182314 cites W203981073 @default.
• W4367182314 cites W2041296416 @default.
• W4367182314 cites W2058562945 @default.
• W4367182314 cites W2112236191 @default.
• W4367182314 cites W2116232743 @default.
• W4367182314 cites W2134942438 @default.
• W4367182314 cites W2157183936 @default.
• W4367182314 cites W2160382843 @default.
• W4367182314 cites W2165370359 @default.
• W4367182314 cites W2167560492 @default.
• W4367182314 cites W2168784615 @default.
• W4367182314 cites W2186262563 @default.
• W4367182314 cites W228600387 @default.
• W4367182314 cites W2366536035 @default.
• W4367182314 cites W2461157957 @default.
• W4367182314 cites W2523133038 @default.
• W4367182314 cites W2537666096 @default.
• W4367182314 cites W2610403529 @default.
• W4367182314 cites W2741009225 @default.
• W4367182314 cites W2752092904 @default.
• W4367182314 cites W2755858023 @default.
• W4367182314 cites W2765212633 @default.
• W4367182314 cites W2768482184 @default.
• W4367182314 cites W2792102603 @default.
• W4367182314 cites W2806558360 @default.
• W4367182314 cites W2811036728 @default.
• W4367182314 cites W2889212189 @default.
• W4367182314 cites W2903361121 @default.
• W4367182314 cites W2904531397 @default.
• W4367182314 cites W2908690972 @default.
• W4367182314 cites W2914759518 @default.
• W4367182314 cites W2954270728 @default.
• W4367182314 cites W2956589719 @default.
• W4367182314 cites W2965620864 @default.
• W4367182314 cites W2969888568 @default.
• W4367182314 cites W2975013431 @default.
• W4367182314 cites W2978935793 @default.
• W4367182314 cites W2989787836 @default.
• W4367182314 cites W3013214688 @default.
• W4367182314 cites W3023597346 @default.
• W4367182314 cites W3026813010 @default.
• W4367182314 cites W3036025215 @default.
• W4367182314 cites W3098926804 @default.
• W4367182314 cites W3174246647 @default.
• W4367182314 cites W3186666722 @default.
• W4367182314 cites W4247691581 @default.
• W4367182314 doi "https://doi.org/10.3390/cancers15092503" @default.
• W4367182314 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37173969" @default.
• W4367182314 hasPublicationYear "2023" @default.
• W4367182314 type Work @default.
• W4367182314 citedByCount "0" @default.
• W4367182314 crossrefType "journal-article" @default.
• W4367182314 hasAuthorship W4367182314A5007118974 @default.
• W4367182314 hasAuthorship W4367182314A5014073957 @default.
• W4367182314 hasAuthorship W4367182314A5015109594 @default.
• W4367182314 hasAuthorship W4367182314A5019526237 @default.
• W4367182314 hasAuthorship W4367182314A5025477516 @default.
• W4367182314 hasAuthorship W4367182314A5052657395 @default.
• W4367182314 hasAuthorship W4367182314A5056148870 @default.
• W4367182314 hasAuthorship W4367182314A5079589784 @default.
• W4367182314 hasAuthorship W4367182314A5080916428 @default.
• W4367182314 hasBestOaLocation W43671823141 @default.
• W4367182314 hasConcept C101070640 @default.
• W4367182314 hasConcept C126322002 @default.
• W4367182314 hasConcept C126838900 @default.
• W4367182314 hasConcept C143409427 @default.
• W4367182314 hasConcept C143998085 @default.
• W4367182314 hasConcept C2778227246 @default.
• W4367182314 hasConcept C2779399171 @default.
• W4367182314 hasConcept C502942594 @default.
• W4367182314 hasConcept C58471807 @default.
• W4367182314 hasConcept C71924100 @default.
• W4367182314 hasConcept C72563966 @default.
• W4367182314 hasConceptScore W4367182314C101070640 @default.
• W4367182314 hasConceptScore W4367182314C126322002 @default.
• W4367182314 hasConceptScore W4367182314C126838900 @default.
• W4367182314 hasConceptScore W4367182314C143409427 @default.

• next