FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4367183973> ?p ?o ?g. }

• W4367183973 abstract "Lysine acetylation modification is a dynamic and reversible post-translational modification, which plays an important role in the metabolism and pathogenicity of pathogenic bacteria. Vibrio alginolyticus is a common pathogenic bacterium in aquaculture, and bile salt can trigger the expression of bacterial virulence. However, little is known about the function of lysine acetylation in V. alginolyticus under bile salt stress. In this study, 1,315 acetylated peptides on 689 proteins were identified in V. alginolyticus under bile salt stress by acetyl-lysine antibody enrichment and high-resolution mass spectrometry. Bioinformatics analysis found that the peptides motif **** A * Kac **** and ******* Kac **** A * were highly conserved, and protein lysine acetylation was involved in regulating various cellular biological processes and maintaining the normal life activities of bacteria, such as ribosome, aminoacyl-tRNA biosynthesis, fatty acid metabolism, two-component system, and bacterial secretion system. Further, 22 acetylated proteins were also found to be related to the virulence of V. alginolyticus under bile salt stress through secretion system, chemotaxis and motility, and adherence. Finally, comparing un-treated and treated with bile salt stress lysine acetylated proteins, it was found that there were 240 overlapping proteins, and found amino sugar and nucleotide sugar metabolism, beta-Lactam resistance, fatty acid degradation, carbon metabolism, and microbial metabolism in diverse environments pathways were significantly enriched in bile salt stress alone. In conclusion, this study is a holistic analysis of lysine acetylation in V. alginolyticus under bile salt stress, especially many virulence factors have also acetylated." @default.
• W4367183973 created "2023-04-28" @default.
• W4367183973 creator A5000572854 @default.
• W4367183973 creator A5020679714 @default.
• W4367183973 creator A5032192447 @default.
• W4367183973 creator A5033450653 @default.
• W4367183973 creator A5039663772 @default.
• W4367183973 creator A5059736823 @default.
• W4367183973 creator A5066590225 @default.
• W4367183973 creator A5081477180 @default.
• W4367183973 creator A5090728786 @default.
• W4367183973 date "2023-04-27" @default.
• W4367183973 modified "2023-09-25" @default.
• W4367183973 title "Holistic analysis of lysine acetylation in aquaculture pathogenic bacteria Vibrio alginolyticus under bile salt stress" @default.
• W4367183973 cites W1579756873 @default.
• W4367183973 cites W1970399546 @default.
• W4367183973 cites W1987805766 @default.
• W4367183973 cites W2017101977 @default.
• W4367183973 cites W2022481196 @default.
• W4367183973 cites W2035911064 @default.
• W4367183973 cites W2080915318 @default.
• W4367183973 cites W2082036588 @default.
• W4367183973 cites W2132552660 @default.
• W4367183973 cites W2146766478 @default.
• W4367183973 cites W2168407603 @default.
• W4367183973 cites W2329881077 @default.
• W4367183973 cites W2333785896 @default.
• W4367183973 cites W2471624339 @default.
• W4367183973 cites W2487838950 @default.
• W4367183973 cites W2497598082 @default.
• W4367183973 cites W2518201392 @default.
• W4367183973 cites W2581803589 @default.
• W4367183973 cites W2604523989 @default.
• W4367183973 cites W2608550167 @default.
• W4367183973 cites W2608973317 @default.
• W4367183973 cites W2616339691 @default.
• W4367183973 cites W2743152982 @default.
• W4367183973 cites W2765578562 @default.
• W4367183973 cites W2766801497 @default.
• W4367183973 cites W2777667033 @default.
• W4367183973 cites W2790677752 @default.
• W4367183973 cites W2795960656 @default.
• W4367183973 cites W2807340022 @default.
• W4367183973 cites W2818491996 @default.
• W4367183973 cites W2826379364 @default.
• W4367183973 cites W2910730299 @default.
• W4367183973 cites W2945386484 @default.
• W4367183973 cites W2950202456 @default.
• W4367183973 cites W2970643537 @default.
• W4367183973 cites W2981626382 @default.
• W4367183973 cites W2985043365 @default.
• W4367183973 cites W3010088835 @default.
• W4367183973 cites W3013886012 @default.
• W4367183973 cites W3014197697 @default.
• W4367183973 cites W3017638283 @default.
• W4367183973 cites W3022690159 @default.
• W4367183973 cites W3095836256 @default.
• W4367183973 cites W3101195279 @default.
• W4367183973 cites W3111070972 @default.
• W4367183973 cites W3134336635 @default.
• W4367183973 cites W3158493599 @default.
• W4367183973 cites W3170070983 @default.
• W4367183973 cites W3177507633 @default.
• W4367183973 cites W3186501474 @default.
• W4367183973 cites W3199643740 @default.
• W4367183973 cites W3199876837 @default.
• W4367183973 cites W3200232281 @default.
• W4367183973 cites W3203130222 @default.
• W4367183973 cites W3210109353 @default.
• W4367183973 cites W3214047937 @default.
• W4367183973 cites W3216736125 @default.
• W4367183973 cites W4210943713 @default.
• W4367183973 cites W4212821511 @default.
• W4367183973 cites W4221123922 @default.
• W4367183973 cites W4294844728 @default.
• W4367183973 doi "https://doi.org/10.3389/fvets.2023.1099255" @default.
• W4367183973 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37180076" @default.
• W4367183973 hasPublicationYear "2023" @default.
• W4367183973 type Work @default.
• W4367183973 citedByCount "0" @default.
• W4367183973 crossrefType "journal-article" @default.
• W4367183973 hasAuthorship W4367183973A5000572854 @default.
• W4367183973 hasAuthorship W4367183973A5020679714 @default.
• W4367183973 hasAuthorship W4367183973A5032192447 @default.
• W4367183973 hasAuthorship W4367183973A5033450653 @default.
• W4367183973 hasAuthorship W4367183973A5039663772 @default.
• W4367183973 hasAuthorship W4367183973A5059736823 @default.
• W4367183973 hasAuthorship W4367183973A5066590225 @default.
• W4367183973 hasAuthorship W4367183973A5081477180 @default.
• W4367183973 hasAuthorship W4367183973A5090728786 @default.
• W4367183973 hasBestOaLocation W43671839731 @default.
• W4367183973 hasConcept C104317684 @default.
• W4367183973 hasConcept C119157956 @default.
• W4367183973 hasConcept C2776016237 @default.
• W4367183973 hasConcept C2776154503 @default.
• W4367183973 hasConcept C2778968793 @default.
• W4367183973 hasConcept C515207424 @default.
• W4367183973 hasConcept C523546767 @default.
• W4367183973 hasConcept C54355233 @default.
• W4367183973 hasConcept C55493867 @default.

• next