FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4367185745> ?p ?o ?g. }

• W4367185745 endingPage "464.e8" @default.
• W4367185745 startingPage "464.e1" @default.
• W4367185745 abstract "BMT CTN 1101 was a Phase III randomized controlled trial comparing reduced-intensity conditioning followed by double unrelated umbilical cord blood transplantation (UCBT) versus HLA-haploidentical related donor bone marrow transplantation (haplo-BMT) for patients with high-risk hematologic malignancies. Here we report the results of a parallel cost-effectiveness analysis of these 2 hematopoietic stem cell transplantation (HCT) techniques. In this study, 368 patients were randomized to unrelated UCBT (n = 186) or haplo-BMT (n = 182). We estimated healthcare utilization and costs using propensity score-matched haplo-BMT recipients from the OptumLabs Data Warehouse for trial participants age <65 years and Medicare claims for participants age ≥65 years. Weibull models were used to estimate 20-year survival. EQ-5D surveys by trial participants were used to estimate quality-adjusted life-years (QALYs). At a 5-year follow-up, survival was 42% for haplo-BMT recipients versus 36% for UCBT recipients (P = .06). Over a 20-year time horizon, haplo-BMT is expected to be more effective (+.63 QALY) and more costly (+$118,953) for persons age <65 years. For those age ≥65 years, haplo-BMT is expected to be more effective and less costly. In one-way uncertainty analyses, for persons age <65, the cost per QALY result was most sensitive to life-years and health state utilities, whereas for those age ≥65, life- years were more influential than costs and health state utilities. Compared to UCBT, haplo-BMT was moderately more cost-effective for patients age <65 years and less costly and more effective for persons age ≥65 years. Haplo-BMT is a fair value choice for commercially insured patients with high-risk leukemia and lymphoma who require HCT. For Medicare enrollees, haplo-BMT is a preferred choice when considering costs and outcomes." @default.
• W4367185745 created "2023-04-28" @default.
• W4367185745 creator A5003177917 @default.
• W4367185745 creator A5014520571 @default.
• W4367185745 creator A5016305379 @default.
• W4367185745 creator A5041346359 @default.
• W4367185745 creator A5046985026 @default.
• W4367185745 creator A5050649888 @default.
• W4367185745 creator A5064006806 @default.
• W4367185745 creator A5066735442 @default.
• W4367185745 creator A5074346702 @default.
• W4367185745 creator A5087861262 @default.
• W4367185745 date "2023-07-01" @default.
• W4367185745 modified "2023-10-16" @default.
• W4367185745 title "Cost-Effectiveness of Unrelated Umbilical Cord Blood Transplantation versus HLA-Haploidentical Related Bone Marrow Transplantation: Evidence from BMT CTN 1101" @default.
• W4367185745 cites W1976873809 @default.
• W4367185745 cites W2004670370 @default.
• W4367185745 cites W2015368967 @default.
• W4367185745 cites W2069140735 @default.
• W4367185745 cites W2111180648 @default.
• W4367185745 cites W2143532751 @default.
• W4367185745 cites W2154146881 @default.
• W4367185745 cites W2539165044 @default.
• W4367185745 cites W2587851012 @default.
• W4367185745 cites W2906351843 @default.
• W4367185745 cites W3033327429 @default.
• W4367185745 cites W3082296557 @default.
• W4367185745 cites W3163736729 @default.
• W4367185745 cites W3212530359 @default.
• W4367185745 doi "https://doi.org/10.1016/j.jtct.2023.04.017" @default.
• W4367185745 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37120135" @default.
• W4367185745 hasPublicationYear "2023" @default.
• W4367185745 type Work @default.
• W4367185745 citedByCount "0" @default.
• W4367185745 crossrefType "journal-article" @default.
• W4367185745 hasAuthorship W4367185745A5003177917 @default.
• W4367185745 hasAuthorship W4367185745A5014520571 @default.
• W4367185745 hasAuthorship W4367185745A5016305379 @default.
• W4367185745 hasAuthorship W4367185745A5041346359 @default.
• W4367185745 hasAuthorship W4367185745A5046985026 @default.
• W4367185745 hasAuthorship W4367185745A5050649888 @default.
• W4367185745 hasAuthorship W4367185745A5064006806 @default.
• W4367185745 hasAuthorship W4367185745A5066735442 @default.
• W4367185745 hasAuthorship W4367185745A5074346702 @default.
• W4367185745 hasAuthorship W4367185745A5087861262 @default.
• W4367185745 hasConcept C126322002 @default.
• W4367185745 hasConcept C168563851 @default.
• W4367185745 hasConcept C203014093 @default.
• W4367185745 hasConcept C2776955114 @default.
• W4367185745 hasConcept C2777408962 @default.
• W4367185745 hasConcept C2911091166 @default.
• W4367185745 hasConcept C71924100 @default.
• W4367185745 hasConceptScore W4367185745C126322002 @default.
• W4367185745 hasConceptScore W4367185745C168563851 @default.
• W4367185745 hasConceptScore W4367185745C203014093 @default.
• W4367185745 hasConceptScore W4367185745C2776955114 @default.
• W4367185745 hasConceptScore W4367185745C2777408962 @default.
• W4367185745 hasConceptScore W4367185745C2911091166 @default.
• W4367185745 hasConceptScore W4367185745C71924100 @default.
• W4367185745 hasFunder F4320332161 @default.
• W4367185745 hasFunder F4320337338 @default.
• W4367185745 hasFunder F4320337351 @default.
• W4367185745 hasIssue "7" @default.
• W4367185745 hasLocation W43671857451 @default.
• W4367185745 hasLocation W43671857452 @default.
• W4367185745 hasOpenAccess W4367185745 @default.
• W4367185745 hasPrimaryLocation W43671857451 @default.
• W4367185745 hasRelatedWork W2154341374 @default.
• W4367185745 hasRelatedWork W2359804617 @default.
• W4367185745 hasRelatedWork W2366793411 @default.
• W4367185745 hasRelatedWork W2392641532 @default.
• W4367185745 hasRelatedWork W2442220036 @default.
• W4367185745 hasRelatedWork W2487150375 @default.
• W4367185745 hasRelatedWork W2606295083 @default.
• W4367185745 hasRelatedWork W2806210973 @default.
• W4367185745 hasRelatedWork W3159250744 @default.
• W4367185745 hasRelatedWork W4256514411 @default.
• W4367185745 hasVolume "29" @default.
• W4367185745 isParatext "false" @default.
• W4367185745 isRetracted "false" @default.
• W4367185745 workType "article" @default.