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- W4367186137 endingPage "100455" @default.
- W4367186137 startingPage "100455" @default.
- W4367186137 abstract "Engineering new functions in the microbiome requires understanding how host genetic control and microbe-microbe interactions shape the microbiome. One key genetic mechanism underlying host control is the immune system. The immune system can promote stability in the composition of the microbiome by reshaping the ecological dynamics of its members, but the degree of stability will depend on the interplay between ecological context, immune system development, and higher-order microbe-microbe interactions. The eco-evolutionary interplay affecting composition and stability should inform the strategies used to engineer new functions in the microbiome. We conclude with recent methodological developments that provide an important path forward for both engineering new functionality in the microbiome and broadly understanding how ecological interactions shape evolutionary processes in complex biological systems." @default.
- W4367186137 created "2023-04-28" @default.
- W4367186137 creator A5014201141 @default.
- W4367186137 creator A5021071256 @default.
- W4367186137 date "2023-06-01" @default.
- W4367186137 modified "2023-10-18" @default.
- W4367186137 title "Evolutionary implications of host genetic control for engineering beneficial microbiomes" @default.
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