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- W4367186672 abstract "We present a sodium trifluoroacetate (CF3CO2Na) mediated copper-catalyzed aza-Michael addition of aromatic amines with activated olefins under mild, aqueous reaction conditions. This simplistic protocol employs a copper catalyst (10 mol%) and water as solvent. This transformation occurs precisely with aromatic substituted amines containing both electron-donating (EDG) and electron-withdrawing (EWG) groups. A broad range of substrates were tested under the optimized conditions, which are producing good to moderate yields." @default.
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- W4367186672 date "2023-06-01" @default.
- W4367186672 modified "2023-09-27" @default.
- W4367186672 title "Sodium Trifluoroacetate mediated Copper-Catalyzed aza-Michael addition of α,β-unsaturated olefins with aromatic amines" @default.
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- W4367186672 doi "https://doi.org/10.1016/j.tetlet.2023.154520" @default.
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