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- W4367292887 abstract "The 2021 Nobel Prize in Physiology or Medicine has gone to David Julius of the University of California, San Francisco, and Ardem Patapoutian of Scripps Research in California for identifying the proteins that detect temperature and touch. “This really unlocks one of the secrets of nature,” Thomas Perlmann, secretary general for the Nobel Assembly , said during the prize announcement in Sweden on Oct. 4. Understanding how we feel temperature and touch began with investigations into the sensation of heat. Julius worked on this puzzle with the help of the molecule capsaicin, which is responsible for the burning sensation that chili peppers deliver. Screening a library of genes from sensory neurons to discover proteins that were sensitive to capsaicin led Julius’s team to one specific ion channel, TRPV1, that reacts to both capsaicin and pain-inducing heat ( Nature 1997, DOI: 10.1038/39807 ). Just a few years later, Julius and Patapoutian" @default.
- W4367292887 created "2023-04-29" @default.
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- W4367292887 date "2021-10-11" @default.
- W4367292887 modified "2023-09-26" @default.
- W4367292887 title "Medicine Nobel celebrates the senses of temperature and touch" @default.
- W4367292887 doi "https://doi.org/10.1021/cen-09937-scicon1" @default.
- W4367292887 hasPublicationYear "2021" @default.
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