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- W4367293205 abstract "To preserve ionic homeostasis (primarily Ca2+, K+, Na+, and Cl-), in the airway smooth muscle (ASM) numerous transporters (channels, exchangers, and pumps) regulate the influx and efflux of these ions. Many of intracellular processes depend on continuous ionic permeation, including exocytosis, contraction, metabolism, transcription, fecundation, proliferation, and apoptosis. These mechanisms are precisely regulated, for instance, through hormonal activity. The lipophilic nature of steroidal hormones allows their free transit into the cell where, in most cases, they occupy their cognate receptor to generate genomic actions. In the sense, estrogens can stimulate development, proliferation, migration, and survival of target cells, including in lung physiology. Non-genomic actions on the other hand do not imply estrogen's intracellular receptor occupation, nor do they initiate transcription and are mostly immediate to the stimulus. Among estrogen's non genomic responses regulation of calcium homeostasis and contraction and relaxation processes play paramount roles in ASM. On the other hand, disruption of calcium homeostasis has been closely associated with some ASM pathological mechanism. Thus, this paper intends to summarize the effects of estrogen on ionic handling proteins in ASM. The considerable diversity, range and power of estrogens regulates ionic homeostasis through genomic and non-genomic mechanisms." @default.
- W4367293205 created "2023-04-29" @default.
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- W4367293205 date "2023-04-26" @default.
- W4367293205 modified "2023-10-01" @default.
- W4367293205 title "Estrogenic Modulation of Ionic Channels, Pumps and Exchangers in Airway Smooth Muscle" @default.
- W4367293205 cites W10525558 @default.
- W4367293205 cites W1186444048 @default.
- W4367293205 cites W1485297825 @default.
- W4367293205 cites W1509765536 @default.
- W4367293205 cites W1590580870 @default.
- W4367293205 cites W1607151736 @default.
- W4367293205 cites W1733775529 @default.
- W4367293205 cites W1805119337 @default.
- W4367293205 cites W1835419280 @default.
- W4367293205 cites W1837596485 @default.
- W4367293205 cites W1873745381 @default.
- W4367293205 cites W1931325223 @default.
- W4367293205 cites W1939531990 @default.
- W4367293205 cites W1953598538 @default.
- W4367293205 cites W1956000379 @default.
- W4367293205 cites W1964557258 @default.
- W4367293205 cites W1965875286 @default.
- W4367293205 cites W1966066124 @default.
- W4367293205 cites W1966238884 @default.
- W4367293205 cites W1967621441 @default.
- W4367293205 cites W1969085416 @default.
- W4367293205 cites W1969210262 @default.
- W4367293205 cites W1976212981 @default.
- W4367293205 cites W1977056617 @default.
- W4367293205 cites W1979986181 @default.
- W4367293205 cites W1981438273 @default.
- W4367293205 cites W1983398269 @default.
- W4367293205 cites W1983780812 @default.
- W4367293205 cites W1984509263 @default.
- W4367293205 cites W1985196243 @default.
- W4367293205 cites W1986791333 @default.
- W4367293205 cites W1988629179 @default.
- W4367293205 cites W1988867422 @default.
- W4367293205 cites W1988990192 @default.
- W4367293205 cites W1989757776 @default.
- W4367293205 cites W1992084571 @default.
- W4367293205 cites W1992821831 @default.
- W4367293205 cites W2000117155 @default.
- W4367293205 cites W2001237115 @default.
- W4367293205 cites W2002333480 @default.
- W4367293205 cites W2002646103 @default.
- W4367293205 cites W2002729412 @default.
- W4367293205 cites W2003013515 @default.
- W4367293205 cites W2003562660 @default.
- W4367293205 cites W2004044410 @default.
- W4367293205 cites W2006036568 @default.
- W4367293205 cites W2006204782 @default.
- W4367293205 cites W2009171847 @default.
- W4367293205 cites W2009468802 @default.
- W4367293205 cites W2011495679 @default.
- W4367293205 cites W2011823146 @default.
- W4367293205 cites W2012186053 @default.
- W4367293205 cites W2013266699 @default.
- W4367293205 cites W2014230117 @default.
- W4367293205 cites W2017793767 @default.
- W4367293205 cites W2021069369 @default.
- W4367293205 cites W2022779434 @default.
- W4367293205 cites W2023766389 @default.
- W4367293205 cites W2024538494 @default.
- W4367293205 cites W2030719220 @default.
- W4367293205 cites W2031195896 @default.
- W4367293205 cites W2032039696 @default.
- W4367293205 cites W2034407790 @default.
- W4367293205 cites W2036145275 @default.
- W4367293205 cites W2037319313 @default.
- W4367293205 cites W2041568486 @default.
- W4367293205 cites W2042874742 @default.
- W4367293205 cites W2045426120 @default.
- W4367293205 cites W2046408444 @default.
- W4367293205 cites W2049309044 @default.
- W4367293205 cites W2049864090 @default.
- W4367293205 cites W2051214272 @default.
- W4367293205 cites W2052040461 @default.
- W4367293205 cites W2053580820 @default.
- W4367293205 cites W2055964134 @default.
- W4367293205 cites W2056934719 @default.
- W4367293205 cites W2063961981 @default.
- W4367293205 cites W2065251939 @default.
- W4367293205 cites W2065795778 @default.
- W4367293205 cites W2072405296 @default.
- W4367293205 cites W2072929449 @default.
- W4367293205 cites W2073663291 @default.
- W4367293205 cites W2074097281 @default.