Matches in SemOpenAlex for { <https://semopenalex.org/work/W4367295984> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W4367295984 endingPage "100119" @default.
- W4367295984 startingPage "100119" @default.
- W4367295984 abstract "Ketamine is a dissociative anaesthetic and a noncompetitive antagonist of the N-methyl-D-aspartate (NMDA) subtype of excitatory amino acid receptors. In cases of Major Depressive Disorder (MDD) and Bipolar Depression, Ketamine may quickly alleviate depressive symptoms. Researchers discovered a comparable decline in suicidal thoughts among MDD patients receiving intravenous boluses in the emergency room. A patient with a severe depressive episode who had previously attempted suicide once and had suicidal thoughts was hospitalised in our department after exhibiting lithium toxicity symptoms and receiving treatment for two months. He received conservative treatment for lithium toxicity and was scheduled to administer Ketamine to reduce his depressive symptoms and suicidal thoughts quickly. Over the course of two weeks, ketamine administration six sessions (the first two intravenous and the latter four by oral route) were given. An excellent clinical response was noted a few hours after the initial session. This improvement was successfully maintained over the course of the next five sessions, reducing depressive symptoms and the risk of suicide. After six sessions, the Hamilton Depression Rating Scale score dropped from 24 to 10. Few side effects were present only during administration and disappeared completely after 2 hours. Findings suggest that Ketamine can be administered safely to a patient with major depressive disorder even in the background of lithium toxicity, to manage depressive symptoms and suicidal thoughts quickly. Venlafaxine and Ketamine are well tolerated when administered simultaneously. When necessary, oral ketamine administration can be used instead of intravenous infusion because it is non-invasive and well-accepted by the patient." @default.
- W4367295984 created "2023-04-29" @default.
- W4367295984 creator A5017474506 @default.
- W4367295984 creator A5038240308 @default.
- W4367295984 creator A5042418987 @default.
- W4367295984 date "2023-06-01" @default.
- W4367295984 modified "2023-09-25" @default.
- W4367295984 title "Switching from parenteral to oral formulation of ketamine in the management of severe depressive episode" @default.
- W4367295984 cites W1877280491 @default.
- W4367295984 cites W2017435851 @default.
- W4367295984 cites W2028884770 @default.
- W4367295984 cites W2089351762 @default.
- W4367295984 cites W2093284812 @default.
- W4367295984 cites W2103255996 @default.
- W4367295984 cites W2108057532 @default.
- W4367295984 cites W2108403304 @default.
- W4367295984 cites W2109334244 @default.
- W4367295984 cites W2111728433 @default.
- W4367295984 cites W2118815581 @default.
- W4367295984 cites W2157040702 @default.
- W4367295984 doi "https://doi.org/10.1016/j.psycr.2023.100119" @default.
- W4367295984 hasPublicationYear "2023" @default.
- W4367295984 type Work @default.
- W4367295984 citedByCount "0" @default.
- W4367295984 crossrefType "journal-article" @default.
- W4367295984 hasAuthorship W4367295984A5017474506 @default.
- W4367295984 hasAuthorship W4367295984A5038240308 @default.
- W4367295984 hasAuthorship W4367295984A5042418987 @default.
- W4367295984 hasBestOaLocation W43672959841 @default.
- W4367295984 hasConcept C118552586 @default.
- W4367295984 hasConcept C126322002 @default.
- W4367295984 hasConcept C139719470 @default.
- W4367295984 hasConcept C15744967 @default.
- W4367295984 hasConcept C162324750 @default.
- W4367295984 hasConcept C194828623 @default.
- W4367295984 hasConcept C2776867660 @default.
- W4367295984 hasConcept C2778541603 @default.
- W4367295984 hasConcept C2778807096 @default.
- W4367295984 hasConcept C2780051608 @default.
- W4367295984 hasConcept C2780733359 @default.
- W4367295984 hasConcept C2780795376 @default.
- W4367295984 hasConcept C2780842732 @default.
- W4367295984 hasConcept C29730261 @default.
- W4367295984 hasConcept C3017944768 @default.
- W4367295984 hasConcept C42219234 @default.
- W4367295984 hasConcept C526869908 @default.
- W4367295984 hasConcept C71924100 @default.
- W4367295984 hasConceptScore W4367295984C118552586 @default.
- W4367295984 hasConceptScore W4367295984C126322002 @default.
- W4367295984 hasConceptScore W4367295984C139719470 @default.
- W4367295984 hasConceptScore W4367295984C15744967 @default.
- W4367295984 hasConceptScore W4367295984C162324750 @default.
- W4367295984 hasConceptScore W4367295984C194828623 @default.
- W4367295984 hasConceptScore W4367295984C2776867660 @default.
- W4367295984 hasConceptScore W4367295984C2778541603 @default.
- W4367295984 hasConceptScore W4367295984C2778807096 @default.
- W4367295984 hasConceptScore W4367295984C2780051608 @default.
- W4367295984 hasConceptScore W4367295984C2780733359 @default.
- W4367295984 hasConceptScore W4367295984C2780795376 @default.
- W4367295984 hasConceptScore W4367295984C2780842732 @default.
- W4367295984 hasConceptScore W4367295984C29730261 @default.
- W4367295984 hasConceptScore W4367295984C3017944768 @default.
- W4367295984 hasConceptScore W4367295984C42219234 @default.
- W4367295984 hasConceptScore W4367295984C526869908 @default.
- W4367295984 hasConceptScore W4367295984C71924100 @default.
- W4367295984 hasIssue "1" @default.
- W4367295984 hasLocation W43672959841 @default.
- W4367295984 hasOpenAccess W4367295984 @default.
- W4367295984 hasPrimaryLocation W43672959841 @default.
- W4367295984 hasRelatedWork W2052665050 @default.
- W4367295984 hasRelatedWork W2149468541 @default.
- W4367295984 hasRelatedWork W2165865776 @default.
- W4367295984 hasRelatedWork W2352219946 @default.
- W4367295984 hasRelatedWork W2557421272 @default.
- W4367295984 hasRelatedWork W2592342712 @default.
- W4367295984 hasRelatedWork W2883869741 @default.
- W4367295984 hasRelatedWork W3211109281 @default.
- W4367295984 hasRelatedWork W4223994262 @default.
- W4367295984 hasRelatedWork W4286664770 @default.
- W4367295984 hasVolume "2" @default.
- W4367295984 isParatext "false" @default.
- W4367295984 isRetracted "false" @default.
- W4367295984 workType "article" @default.