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• W4367298467 abstract "Derivatives of lactam, cyclic urea and carbamate were explored as aniline amide replacements in a series of phthalazinone-based ROCK inhibitors. Potent ROCK2 inhibitors such as 22 were identified with excellent overall kinase selectivity as well as good isoform selectivity over ROCK1." @default.
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• W4367298467 date "2023-05-01" @default.
• W4367298467 modified "2023-09-30" @default.
• W4367298467 title "Phthalazinone-based lactams and cyclic ureas as ROCK2 selective inhibitors" @default.
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• W4367298467 doi "https://doi.org/10.1016/j.bmcl.2023.129304" @default.
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