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• W4367300045 endingPage "2081" @default.
• W4367300045 startingPage "2081" @default.
• W4367300045 abstract "In the present study, a novel water-soluble polysaccharide (DNP−1) was isolated and purified from the root of Duhaldea nervosa via column chromatography. Structural analyses indicated that DNP−1 had a linear backbone consisting of (2→1)-linked β-D- fructofuranosyl residues, ending with a (2→1) bonded α-D-glucopyranose. DNP−1 was a homogeneous polysaccharide with an average molecular weight of 3.7 kDa. Furthermore, the anti-inflammatory activity of DNP−1 was investigated in vitro. The concentration of pro-inflammatory cytokines, including NO, TNF-α, MCP-1, IL-2, and IL-6, in the DNP−1 treatment group was suppressed in LPS-induced RAW 264.7 cells. DNP−1 was able to improve inflammatory injury by inhibiting the secretion of pro-inflammatory cytokines. These investigations into this polysaccharide from the root of Duhaldea nervosa provide a scientific basis for the further development of this plant. The results indicate that this Duhaldea nervosa polysaccharide could be used as a potential natural source for the treatment of inflammatory injury." @default.
• W4367300045 created "2023-04-29" @default.
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• W4367300045 date "2023-04-27" @default.
• W4367300045 modified "2023-09-30" @default.
• W4367300045 title "Structural Characterization and Anti-Inflammatory Activity of a Novel Polysaccharide from Duhaldea nervosa" @default.
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• W4367300045 doi "https://doi.org/10.3390/polym15092081" @default.
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