FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4367303209> ?p ?o ?g. }

• W4367303209 abstract "<h3>Objective:</h3> To determine differences in demographic and clinical profile of South Asian vs. non-South Asian patients with Parkinson’s disease (PD) undergoing deep brain stimulation (DBS). <h3>Background:</h3> The majority of knowledge of PD has been gleaned from the discoveries made in familial and/or sporadic forms of PD in the Caucasian population. The transferability and the clinical utility of such biochemical and genetic discoveries to other ethnically diverse populations are unknown, with the South Asian population being underrepresented in PD research. <h3>Design/Methods:</h3> We performed a retrospective review of South Asian vs. non-South Asian PD patients undergoing STN-DBS between 2017–2022. Demographic data and clinical data were obtained. Pre-operative OFF/ON evaluation (dopamine challenge), neuropsychological testing scores (Dementia Rating Scale-2), motor and non-motor complaints were compared between the two groups using a Student’s T-test or chi-squared test as appropriate. <h3>Results:</h3> We compared data from 9 South Asian and 21 non-South Asian PD patients. Demographic characteristics were not different between the two groups. Alcohol use was less common in the South Asian population with a trend towards significance (88% never used vs. 57%, respectively, p = 0.09). At the pre-DBS evaluation, there was no difference in percent change in Unified Parkinson’s Disease Rating Scale (UPDRS) scores comparing OFF and ON evaluations, nor differences in DRS-2 scores. About 86% of non-South Asian patients complained of tremor pre-DBS, compared with only 44% in the South Asian group (p = 0.02). REM Behavior Disorder (RBD) was also less commonly reported in the South Asian vs. non-South Asian group (0% vs. 43%, respectively, p = 0.02). <h3>Conclusions:</h3> In this pilot study, we found differences in the clinical profile of South Asian vs. non-South Asian PD patients. Larger studies are needed to further examine these differences in the South Asian population which may lead to improved care and treatment in this group of patients. <b>Disclosure:</b> Mr. Srinivasan has nothing to disclose. Dr. Hargreaves has nothing to disclose. Ms. Caputo has nothing to disclose. Jasdeep Hundal has received research support from Rutgers University CAHBIR/BHI. Jasdeep Hundal has received research support from Horizon BCBS. Jasdeep Hundal has received research support from National Cancer Institute (NCI). Jasdeep Hundal has received research support from National Institute of Health/NIA. Dr. Danish has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for medtronic. Dr. Chen has nothing to disclose. Dr. Pal has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Guidepoint. Dr. Pal has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Kyowa Kirin. Dr. Pal has stock in Baudax Bio. The institution of Dr. Pal has received research support from National Institutes of Health. The institution of Dr. Pal has received research support from Parkinson’s Foundation." @default.
• W4367303209 created "2023-04-29" @default.
• W4367303209 creator A5010639899 @default.
• W4367303209 creator A5014257220 @default.
• W4367303209 creator A5018487972 @default.
• W4367303209 creator A5037812883 @default.
• W4367303209 creator A5042687733 @default.
• W4367303209 creator A5056824555 @default.
• W4367303209 creator A5072516098 @default.
• W4367303209 date "2023-04-25" @default.
• W4367303209 modified "2023-10-01" @default.
• W4367303209 title "Demographic and Clinical Profile of South Asian vs. non-South Asian Patients with Parkinson’s disease (P6-11.003)" @default.
• W4367303209 doi "https://doi.org/10.1212/wnl.0000000000202461" @default.
• W4367303209 hasPublicationYear "2023" @default.
• W4367303209 type Work @default.
• W4367303209 citedByCount "0" @default.
• W4367303209 crossrefType "proceedings-article" @default.
• W4367303209 hasAuthorship W4367303209A5010639899 @default.
• W4367303209 hasAuthorship W4367303209A5014257220 @default.
• W4367303209 hasAuthorship W4367303209A5018487972 @default.
• W4367303209 hasAuthorship W4367303209A5037812883 @default.
• W4367303209 hasAuthorship W4367303209A5042687733 @default.
• W4367303209 hasAuthorship W4367303209A5056824555 @default.
• W4367303209 hasAuthorship W4367303209A5072516098 @default.
• W4367303209 hasConcept C126322002 @default.
• W4367303209 hasConcept C138496976 @default.
• W4367303209 hasConcept C15744967 @default.
• W4367303209 hasConcept C1862650 @default.
• W4367303209 hasConcept C2549261 @default.
• W4367303209 hasConcept C2779134260 @default.
• W4367303209 hasConcept C2779483572 @default.
• W4367303209 hasConcept C2779734285 @default.
• W4367303209 hasConcept C2780906993 @default.
• W4367303209 hasConcept C2908647359 @default.
• W4367303209 hasConcept C3019281177 @default.
• W4367303209 hasConcept C71924100 @default.
• W4367303209 hasConcept C83849319 @default.
• W4367303209 hasConcept C95457728 @default.
• W4367303209 hasConcept C99454951 @default.
• W4367303209 hasConceptScore W4367303209C126322002 @default.
• W4367303209 hasConceptScore W4367303209C138496976 @default.
• W4367303209 hasConceptScore W4367303209C15744967 @default.
• W4367303209 hasConceptScore W4367303209C1862650 @default.
• W4367303209 hasConceptScore W4367303209C2549261 @default.
• W4367303209 hasConceptScore W4367303209C2779134260 @default.
• W4367303209 hasConceptScore W4367303209C2779483572 @default.
• W4367303209 hasConceptScore W4367303209C2779734285 @default.
• W4367303209 hasConceptScore W4367303209C2780906993 @default.
• W4367303209 hasConceptScore W4367303209C2908647359 @default.
• W4367303209 hasConceptScore W4367303209C3019281177 @default.
• W4367303209 hasConceptScore W4367303209C71924100 @default.
• W4367303209 hasConceptScore W4367303209C83849319 @default.
• W4367303209 hasConceptScore W4367303209C95457728 @default.
• W4367303209 hasConceptScore W4367303209C99454951 @default.
• W4367303209 hasLocation W43673032091 @default.
• W4367303209 hasOpenAccess W4367303209 @default.
• W4367303209 hasPrimaryLocation W43673032091 @default.
• W4367303209 hasRelatedWork W1984911966 @default.
• W4367303209 hasRelatedWork W2007990932 @default.
• W4367303209 hasRelatedWork W2013354290 @default.
• W4367303209 hasRelatedWork W2418960833 @default.
• W4367303209 hasRelatedWork W2968429331 @default.
• W4367303209 hasRelatedWork W3088070796 @default.
• W4367303209 hasRelatedWork W3209291259 @default.
• W4367303209 hasRelatedWork W3211057825 @default.
• W4367303209 hasRelatedWork W4312538081 @default.
• W4367303209 hasRelatedWork W2550787946 @default.
• W4367303209 isParatext "false" @default.
• W4367303209 isRetracted "false" @default.
• W4367303209 workType "article" @default.