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- W4367304189 abstract "<h3>Objective:</h3> Describe the characteristics of caregivers of people with multiple sclerosis (PwMS) and explore the associations between cognitive and clinical variables of PwMS, and caregiver’s quality of life (QoL) <h3>Background:</h3> Caring for PwMS may negatively impact on several aspects of the caregiver’s QoL. <h3>Design/Methods:</h3> 50 PwMS and their respective caregivers were included. PwMS: 35 women (70%); Relapsing-remitting: 41, Secondary-progressive: 6, Primary-progressive: 3. Age: 47.08±14.43; Education: 14.38±2.91; Physical disability: 4.09±2.65. Depression: 14.30±10.33, Fatigue: 4.01±1.81. Caregivers: 30 women (53%); Age: 53.58±14.05; Education: 14.88±3.08. Outcomes: Expanded Disability Status Scale, Fatigue Severity Scale, Beck Depression Inventory II, Pfeffer Functional Activity Questionnaire, Caregiver Health-related Quality of life in MS (CareQoL-MS), Resource Utilization in Dementia Questionnaire (RUD). Statistical analysis: Descriptive analysis and Pearson’s correlation were performed. <h3>Results:</h3> Caregivers’ characteristics: 14% of caregivers report presence of depression (6.74±4.47) and 46% of anxiety (7.64±6.51). 67% caregiver currently live with PwEM; The relationships of the caregiver and PwMS reported are: 44% spouses, 20% parents, 12% siblings, son/daughter 6%, friend 4%, 14% other. Significant correlations were reported between caregiver’s QoL and PwMS cognition in processing speed (<i>r=</i>0.644, <i>p=</i>0.00), verbal memory (<i>r=</i>0.437, <i>p=</i>0.000), and visual memory (<i>r=</i>0.418, <i>p=</i>0.000). The associations between PwMS cognition in processing speed (<i>r=</i>0.352, <i>p=</i>0.012), verbal memory (<i>r=</i>0.385, <i>p=</i>0.006), and visual memory (<i>r=</i>0.378, <i>p=</i>0.007), and caregiver’s anxiety are modest. No association with caregiver’s depression is reported. Significant negative correlations are shown between the caregiver’s QoL and the patient’s physical disability (r=0.546, p=0.00), the number of days of assistance in basic activities of daily living (<i>r=</i>0.537, p=0.00), the number of days of assistance in instrumental activities of daily living (<i>r</i>=0.484, <i>p</i>=0.00) and functional dependency (<i>r</i>=0.683, <i>p</i>=0.00). <h3>Conclusions:</h3> Better cognitive performance of the PwMS is associated with a lower level of anxiety and better QoL in caregivers. QoL of caregivers is also correlated with lower functional dependency of PwMS and the time of care. <b>Disclosure:</b> Miss Bardoneschi has nothing to disclose. Maria Sol Román has nothing to disclose. Flavia Ferrandina has nothing to disclose. Dr. Bauer has nothing to disclose. Dr. Rosa has received personal compensation in the range of $0-$499 for serving on a Speakers Bureau for Merck. Maria Laura Saladino has nothing to disclose. Fernando Caceres has nothing to disclose. Sandra Vanotti has received research support from Merck S.A.,Buenos Aires, Argentina, an affiliate Merck S.A.,Buenos Aires, Argentina, an affiliate of Merck KGaA, Darmstadt, Germany Merck KGaA, Darmstadt, Germany." @default.
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- W4367304189 date "2023-04-25" @default.
- W4367304189 modified "2023-09-29" @default.
- W4367304189 title "Quality of life of caregivers of people with multiple sclerosis: Correlations between cognition, clinical variables, and functional dependency (P4-12.009)" @default.
- W4367304189 doi "https://doi.org/10.1212/wnl.0000000000202480" @default.
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