Matches in SemOpenAlex for { <https://semopenalex.org/work/W4367304523> ?p ?o ?g. }
Showing items 1 to 46 of
46
with 100 items per page.
- W4367304523 abstract "<h3>Objective:</h3> Measure visual outcomes in high-risk idiopathic intracranial hypertension (IIH), with particular attention to medical or surgical treatment course and disease recurrence. <h3>Background:</h3> In IIH, presentations with BMI >40, high-grade papilledema, worse visual field mean deviation (VFMD), and worse visual acuity are associated with worse visual outcomes. In the absence of randomized data on high-risk patients, surgery is often recommended, but risks complications, infections, or surgical revision. <h3>Design/Methods:</h3> We retrospectively reviewed the charts of all IIH patients who presented to 3 providers between April 2019 and April 2022 with grade IV or V papilledema. Patients were treated at the discretion of their neuro-ophthalmologist. Outcomes were stratified by presenting VFMD. <h3>Results:</h3> 11 patients were evaluated. Average age was 25.8 years, 10/11 were female, and average BMI was 38.3 kg/m2. On presentation, VA was 20/30 or worse in 9/11 patients, but improved to 20/20 or better in 9/11 patients. Average presenting VFMD was −13.8 dB, but improved by an average of 7.1 dB in those with initial VFMD worse than −7.0 dB and 2.1 dB in those with initial VFMD better than −7.0 dB. 2 patients met published criteria for “fulminant” IIH, but both improved to 20/20 acuity OU with significant VFMD improvements on medical therapy alone. All patients received acetazolamide with rapid dose escalation. Average maximum dose was 2.75 g per day. 2 also received topiramate. 1 patient received a ventriculoperitoneal shunt 3 days after presentation. 1 patient received an optic nerve sheath fenestration 15 days after presentation. 1 patient on medical therapy had recurrent disease over an average of 352 days of follow up. <h3>Conclusions:</h3> Select patients with high-risk or “fulminant” IIH may be successfully managed without surgery. These patients required close monitoring and aggressive medical therapy. Reduced visual acuity on presentation recovered well in most patients. Larger cohorts with longer follow-up are needed. <b>Disclosure:</b> Dr. Gluckstein has nothing to disclose. An immediate family member of Dr. Rizzo has received personal compensation for serving as an employee of LIfeBiosciences. Dr. Rizzo has received intellectual property interests from a discovery or technology relating to health care. Dr. Rizzo has received intellectual property interests from a discovery or technology relating to health care. Dr. Chen has nothing to disclose." @default.
- W4367304523 created "2023-04-29" @default.
- W4367304523 creator A5010796710 @default.
- W4367304523 creator A5030512665 @default.
- W4367304523 creator A5075517358 @default.
- W4367304523 date "2023-04-25" @default.
- W4367304523 modified "2023-09-27" @default.
- W4367304523 title "Select Patients with High-Risk IIH May Be Managed with Medical Therapy Alone (P2-9.009)" @default.
- W4367304523 doi "https://doi.org/10.1212/wnl.0000000000202577" @default.
- W4367304523 hasPublicationYear "2023" @default.
- W4367304523 type Work @default.
- W4367304523 citedByCount "0" @default.
- W4367304523 crossrefType "proceedings-article" @default.
- W4367304523 hasAuthorship W4367304523A5010796710 @default.
- W4367304523 hasAuthorship W4367304523A5030512665 @default.
- W4367304523 hasAuthorship W4367304523A5075517358 @default.
- W4367304523 hasConcept C141071460 @default.
- W4367304523 hasConcept C187212893 @default.
- W4367304523 hasConcept C2776367607 @default.
- W4367304523 hasConcept C2778107024 @default.
- W4367304523 hasConcept C2778257484 @default.
- W4367304523 hasConcept C2780954326 @default.
- W4367304523 hasConcept C71924100 @default.
- W4367304523 hasConceptScore W4367304523C141071460 @default.
- W4367304523 hasConceptScore W4367304523C187212893 @default.
- W4367304523 hasConceptScore W4367304523C2776367607 @default.
- W4367304523 hasConceptScore W4367304523C2778107024 @default.
- W4367304523 hasConceptScore W4367304523C2778257484 @default.
- W4367304523 hasConceptScore W4367304523C2780954326 @default.
- W4367304523 hasConceptScore W4367304523C71924100 @default.
- W4367304523 hasLocation W43673045231 @default.
- W4367304523 hasOpenAccess W4367304523 @default.
- W4367304523 hasPrimaryLocation W43673045231 @default.
- W4367304523 hasRelatedWork W1544680356 @default.
- W4367304523 hasRelatedWork W1976955507 @default.
- W4367304523 hasRelatedWork W1986479967 @default.
- W4367304523 hasRelatedWork W1988481139 @default.
- W4367304523 hasRelatedWork W2007241261 @default.
- W4367304523 hasRelatedWork W2042410635 @default.
- W4367304523 hasRelatedWork W2044415719 @default.
- W4367304523 hasRelatedWork W2054821148 @default.
- W4367304523 hasRelatedWork W2121353355 @default.
- W4367304523 hasRelatedWork W2405469204 @default.
- W4367304523 isParatext "false" @default.
- W4367304523 isRetracted "false" @default.
- W4367304523 workType "article" @default.