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• W4367307533 abstract "Abstract Background: The Triglyceride-glucose (TyG) index is considered to be a simple and reliable surrogate for insulin resistance and an independent predictor of metabolic syndrome. Due to a lack of data on the TyG index in acute pancreatitis (AP). we aimed to investigate the predictive value of the TyG index for the prognosis of severe AP. Methods: The medical data of subjects diagnosed with acute pancreatitis who were hospitalized at Wannan Medical College Yiji Shan Hospital from January 2020 to December 2022 were retrieved from the database and retrospectively analyzed. Patients were divided into two groups according to the Atlanta classification. The TyG index was calculated as follows: ln [fasting triglycerides (mg/dL) × fasting plasma glucose (mg/ dL)/2]. The major adverse outcome was disease severity, intensive care unit admission, and mortality. Results: A total of 404 patients with acute pancreatitis were included, of whom 59 developed severe acute pancreatitis. The TyG index was higher in the SAP group than in the non-SAP group (8.44 ± 1.53 vs 7.58 ± 1.34, p < 0.05). The area under the TyG index for predicting severe AP was 0.670 (95% CI 0.595 - 0.745, p < 0.05). In multivariate logistic regression, after adjusting for covariates, the TyG index was an independent risk factor for either intensive care unit admission (OR: 1.358, 95% CI: 1.101-1.676, P＜0.05) or severe AP (OR: 1.513, 95% CI: 1.247-1.834, P＜0.05). Conclusions: The TyG index is an independent prognostic factor in patients with acute pancreatitis." @default.
• W4367307533 created "2023-04-29" @default.
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• W4367307533 date "2023-04-28" @default.
• W4367307533 modified "2023-09-27" @default.
• W4367307533 title "Elevated serum high triglyceride-glucose index is Independently Associated with poor prognosis in patients with acute pancreatitis" @default.
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• W4367307533 doi "https://doi.org/10.21203/rs.3.rs-2864101/v1" @default.
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