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- W4367312229 endingPage "3798" @default.
- W4367312229 startingPage "3798" @default.
- W4367312229 abstract "Quantitative nuclear imaging techniques are in high demand for various disease diagnostics and cancer theranostics. The non-invasive imaging modality requires radiotracing through the radioactive decay emission of the radionuclide. Current preclinical and clinical radiotracers, so-called nuclear imaging probes, are radioisotope-labeled small molecules. Liposomal radiotracers have been rapidly developing as novel nuclear imaging probes. The physicochemical properties and structural characteristics of liposomes have been elucidated to address their long circulation and stability as radiopharmaceuticals. Various radiolabeling methods for synthesizing radionuclides onto liposomes and synthesis strategies have been summarized to render them biocompatible and enable specific targeting. Through a variety of radionuclide labeling methods, radiolabeled liposomes for use as nuclear imaging probes can be obtained for in vivo biodistribution and specific targeting studies. The advantages of radiolabeled liposomes including their use as potential clinical nuclear imaging probes have been highlighted. This review is a comprehensive overview of all recently published liposomal SPECT and PET imaging probes." @default.
- W4367312229 created "2023-04-29" @default.
- W4367312229 creator A5011823379 @default.
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- W4367312229 creator A5039079103 @default.
- W4367312229 creator A5083987765 @default.
- W4367312229 creator A5089176308 @default.
- W4367312229 date "2023-04-28" @default.
- W4367312229 modified "2023-10-14" @default.
- W4367312229 title "Radiolabeled Liposomes for Nuclear Imaging Probes" @default.
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