Matches in SemOpenAlex for { <https://semopenalex.org/work/W4367316833> ?p ?o ?g. }
- W4367316833 endingPage "73" @default.
- W4367316833 startingPage "73" @default.
- W4367316833 abstract "Traumas and infectious diseases of the eye play a leading role in the development of corneal blindness responsible for 1.5-2 million cases of vision loss per year. To date, the issue of reducing the incidence of fungal keratitis is acute and needs to be solved worldwide. Trauma as a risk factor for corneal fungal disease is thought to be prevalent in developing countries due to agricultural involvement, while in developed countries the onset of the disease is predisposed by medical advances such as contact vision correction and modern ophthalmic surgery. Thorough analysis of the pathogenesis gives the possibility to describe the action of fungal enzymes, biofilm formation, and the resistance mechanism, which on the one hand explains the aggressive course of the disease and difficulties in its diagnosis, and on the other hand, it encourages searching for new methods of diagnosis and treatment. The non-specific clinical picture of fungal keratitis, the variety and availability of antibiotics nowadays become an obstacle for rapid detection of this pathology. Low public awareness and late visit to an ophthalmologist are also a barrier to successful combating the increasing incidence of fungal keratitis. Belated diagnosis, increasing resistance of fungi to antibiotics, and lack of registered antifungal ophthalmic drugs justify poor treatment efficacy resulting in decreased visual acuity or vision loss. Existing diagnostic methods need systematization and detailed comparison, identifying the advantages and disadvantages of each. This review considers causative agents and their influence on pathogenesis of the disease, describes difficulties of fungal keratitis diagnosis and possible ways of overcoming these problems using new developments, and also outlines further prospects of research in this direction." @default.
- W4367316833 created "2023-04-29" @default.
- W4367316833 creator A5009181100 @default.
- W4367316833 creator A5090252831 @default.
- W4367316833 date "2023-04-28" @default.
- W4367316833 modified "2023-09-25" @default.
- W4367316833 title "Modern Technologies in Diagnosis of Fungal Keratitis (Review)" @default.
- W4367316833 cites W156325594 @default.
- W4367316833 cites W1945448290 @default.
- W4367316833 cites W1966049729 @default.
- W4367316833 cites W1976480045 @default.
- W4367316833 cites W1980993991 @default.
- W4367316833 cites W1983462777 @default.
- W4367316833 cites W1984813184 @default.
- W4367316833 cites W1989679050 @default.
- W4367316833 cites W1994976851 @default.
- W4367316833 cites W2012150744 @default.
- W4367316833 cites W2015411518 @default.
- W4367316833 cites W2020180681 @default.
- W4367316833 cites W2021156150 @default.
- W4367316833 cites W2028504969 @default.
- W4367316833 cites W2053320686 @default.
- W4367316833 cites W2062753318 @default.
- W4367316833 cites W2064185190 @default.
- W4367316833 cites W2069181705 @default.
- W4367316833 cites W2088392576 @default.
- W4367316833 cites W2088824920 @default.
- W4367316833 cites W2090094882 @default.
- W4367316833 cites W2095648038 @default.
- W4367316833 cites W2098947340 @default.
- W4367316833 cites W2130479696 @default.
- W4367316833 cites W2144386074 @default.
- W4367316833 cites W2153077179 @default.
- W4367316833 cites W2156995984 @default.
- W4367316833 cites W2180471991 @default.
- W4367316833 cites W2225007036 @default.
- W4367316833 cites W2270336197 @default.
- W4367316833 cites W2315730225 @default.
- W4367316833 cites W2410267011 @default.
- W4367316833 cites W2509734169 @default.
- W4367316833 cites W2524170467 @default.
- W4367316833 cites W2604635152 @default.
- W4367316833 cites W2607103004 @default.
- W4367316833 cites W2611540963 @default.
- W4367316833 cites W2625924235 @default.
- W4367316833 cites W2766312362 @default.
- W4367316833 cites W2767031614 @default.
- W4367316833 cites W2775559950 @default.
- W4367316833 cites W2789009981 @default.
- W4367316833 cites W2793608126 @default.
- W4367316833 cites W2794482948 @default.
- W4367316833 cites W2886749263 @default.
- W4367316833 cites W2888908701 @default.
- W4367316833 cites W2889022558 @default.
- W4367316833 cites W2889601304 @default.
- W4367316833 cites W2891999566 @default.
- W4367316833 cites W2898378937 @default.
- W4367316833 cites W2911013119 @default.
- W4367316833 cites W2944257378 @default.
- W4367316833 cites W2945625818 @default.
- W4367316833 cites W2949239745 @default.
- W4367316833 cites W2976332420 @default.
- W4367316833 cites W2978582090 @default.
- W4367316833 cites W2981240979 @default.
- W4367316833 cites W2988933671 @default.
- W4367316833 cites W2999371982 @default.
- W4367316833 cites W3004627029 @default.
- W4367316833 cites W3008717712 @default.
- W4367316833 cites W3042340397 @default.
- W4367316833 cites W3088475213 @default.
- W4367316833 cites W3094023869 @default.
- W4367316833 cites W3107422974 @default.
- W4367316833 cites W3132491971 @default.
- W4367316833 cites W3133049688 @default.
- W4367316833 cites W3133098898 @default.
- W4367316833 cites W3187158005 @default.
- W4367316833 cites W3197357928 @default.
- W4367316833 cites W3197579264 @default.
- W4367316833 cites W3203141744 @default.
- W4367316833 cites W3208072175 @default.
- W4367316833 cites W3209994877 @default.
- W4367316833 cites W3210137404 @default.
- W4367316833 cites W3212118097 @default.
- W4367316833 cites W3214509625 @default.
- W4367316833 cites W4221047883 @default.
- W4367316833 cites W4225384885 @default.
- W4367316833 cites W4239515908 @default.
- W4367316833 cites W78272413 @default.
- W4367316833 doi "https://doi.org/10.17691/stm2023.15.2.07" @default.
- W4367316833 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37389020" @default.
- W4367316833 hasPublicationYear "2023" @default.
- W4367316833 type Work @default.
- W4367316833 citedByCount "0" @default.
- W4367316833 crossrefType "journal-article" @default.
- W4367316833 hasAuthorship W4367316833A5009181100 @default.
- W4367316833 hasAuthorship W4367316833A5090252831 @default.
- W4367316833 hasBestOaLocation W43673168331 @default.
- W4367316833 hasConcept C118487528 @default.