Matches in SemOpenAlex for { <https://semopenalex.org/work/W4367319250> ?p ?o ?g. }
- W4367319250 endingPage "1083" @default.
- W4367319250 startingPage "1083" @default.
- W4367319250 abstract "Human cytomegalovirus (HCMV) exploits host mitochondrial function to promote viral replication. HCMV gene products have been described to directly interact and alter functional or structural aspects of host mitochondria. Current antivirals against HCMV, such as ganciclovir and letermovir, are designed against viral targets. Concerns with the current antivirals include toxicity and viral resistance. Targeting host mitochondrial function is a promising alternative or complimentary antiviral approach as (1) drugs targeting host mitochondrial function interact with host targets, minimizing viral resistance, and (2) host mitochondrial metabolism plays key roles in HCMV replication. This review describes how HCMV alters mitochondrial function and highlights pharmacological targets that can be exploited for novel antiviral development." @default.
- W4367319250 created "2023-04-29" @default.
- W4367319250 creator A5033206494 @default.
- W4367319250 creator A5064337012 @default.
- W4367319250 date "2023-04-28" @default.
- W4367319250 modified "2023-10-18" @default.
- W4367319250 title "Targeting the Host Mitochondria as a Novel Human Cytomegalovirus Antiviral Strategy" @default.
- W4367319250 cites W1461437644 @default.
- W4367319250 cites W1500300692 @default.
- W4367319250 cites W1902278985 @default.
- W4367319250 cites W1965703031 @default.
- W4367319250 cites W1985380245 @default.
- W4367319250 cites W1990412352 @default.
- W4367319250 cites W2003624793 @default.
- W4367319250 cites W2012442095 @default.
- W4367319250 cites W2020939886 @default.
- W4367319250 cites W2026144912 @default.
- W4367319250 cites W2026419574 @default.
- W4367319250 cites W2036455711 @default.
- W4367319250 cites W2039193490 @default.
- W4367319250 cites W2051551158 @default.
- W4367319250 cites W2054776071 @default.
- W4367319250 cites W2059623168 @default.
- W4367319250 cites W2060274140 @default.
- W4367319250 cites W2061059838 @default.
- W4367319250 cites W2061114093 @default.
- W4367319250 cites W2066379321 @default.
- W4367319250 cites W2070423619 @default.
- W4367319250 cites W2071449688 @default.
- W4367319250 cites W2082240840 @default.
- W4367319250 cites W2086333472 @default.
- W4367319250 cites W2088108607 @default.
- W4367319250 cites W2092333948 @default.
- W4367319250 cites W2111139068 @default.
- W4367319250 cites W2114795453 @default.
- W4367319250 cites W2115394517 @default.
- W4367319250 cites W2118497859 @default.
- W4367319250 cites W2118531942 @default.
- W4367319250 cites W2119437574 @default.
- W4367319250 cites W2126711569 @default.
- W4367319250 cites W2130187195 @default.
- W4367319250 cites W2132869468 @default.
- W4367319250 cites W2133735818 @default.
- W4367319250 cites W2136516946 @default.
- W4367319250 cites W2136526151 @default.
- W4367319250 cites W2139068641 @default.
- W4367319250 cites W2139153271 @default.
- W4367319250 cites W2140691264 @default.
- W4367319250 cites W2141935262 @default.
- W4367319250 cites W2143681046 @default.
- W4367319250 cites W2147999070 @default.
- W4367319250 cites W2152793164 @default.
- W4367319250 cites W2154938348 @default.
- W4367319250 cites W2164882663 @default.
- W4367319250 cites W2176430082 @default.
- W4367319250 cites W2258308895 @default.
- W4367319250 cites W2278896297 @default.
- W4367319250 cites W2285523483 @default.
- W4367319250 cites W2335536436 @default.
- W4367319250 cites W2395441025 @default.
- W4367319250 cites W2508810285 @default.
- W4367319250 cites W2518837957 @default.
- W4367319250 cites W2519401768 @default.
- W4367319250 cites W2530872875 @default.
- W4367319250 cites W2572741715 @default.
- W4367319250 cites W2586320694 @default.
- W4367319250 cites W2614848979 @default.
- W4367319250 cites W2712679337 @default.
- W4367319250 cites W2753234815 @default.
- W4367319250 cites W2757407086 @default.
- W4367319250 cites W2781731842 @default.
- W4367319250 cites W2790615752 @default.
- W4367319250 cites W2792151102 @default.
- W4367319250 cites W2900808325 @default.
- W4367319250 cites W2904551338 @default.
- W4367319250 cites W2904715359 @default.
- W4367319250 cites W2912764509 @default.
- W4367319250 cites W2914578369 @default.
- W4367319250 cites W2914976966 @default.
- W4367319250 cites W2944315478 @default.
- W4367319250 cites W2961401903 @default.
- W4367319250 cites W2963402728 @default.
- W4367319250 cites W2964442492 @default.
- W4367319250 cites W2971477903 @default.
- W4367319250 cites W2980622391 @default.
- W4367319250 cites W2981369289 @default.
- W4367319250 cites W2983089118 @default.
- W4367319250 cites W3014440113 @default.
- W4367319250 cites W3016643255 @default.
- W4367319250 cites W3043817571 @default.
- W4367319250 cites W3044264283 @default.
- W4367319250 cites W3045699143 @default.
- W4367319250 cites W3047182371 @default.
- W4367319250 cites W3080884150 @default.
- W4367319250 cites W3090675856 @default.
- W4367319250 cites W3093637584 @default.
- W4367319250 cites W3095597907 @default.
- W4367319250 cites W3154188917 @default.