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- W4367331472 abstract "SUMMARY This open, multinational, randomised, parallel‐group, six‐month extension conducted in the Swedish centres of a previous six‐month study compared the costs of a total of 12 months of treatment with budesonide/formoterol in a single inhaler with budesonide plus formoterol separate inhalers in 320 adults with asthma. Patients received budesonide/formoterol (Symbicort® Turbuhaler®) 160/4.5 mg delivered doses, two inhalations b.i.d., or corresponding doses of budesonide (Pulmicort® Turbuhaler) plus formoterol (Oxis® Turbuhaler). Direct costs and indirect costs were estimated. Budesonide/formoterol treatment was associated with reduced healthcare service utilisation and statistically significant reductions in direct (SEK1595, p=0.0004) and total costs (SEK1884, p=0.043) per person per year compared with budesonide plus formoterol. Budesonide/formoterol reduced the average annual emergency room admission cost per person by SEK489.7 (31% of direct cost reduction) and physician costs by SEK235.4 (15%). The direct cost of study, relief and other medication was reduced by SEK893.8 (47% of total reduction). There were no statistically significant differences in efficacy and safety parameters following treatment with budesonide/formoterol from single or separate inhalers, other than a significantly lower proportion of withdrawals with the single inhaler (9.2% vs 19.4%, p=0.008). In summary, budesonide/formoterol treatment from a single inhaler reduced 12‐month treatment costs compared with separate inhalers, while maintaining at least as good control of asthma." @default.
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- W4367331472 date "2003-10-01" @default.
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- W4367331472 title "BUDESONIDE/FORMOTEROL IN A SINGLE INHALER (SYMBICORT®) REDUCES HEALTHCARE COSTS COMPARED WITH SEPARATE INHALERS IN THE TREATMENT OF ASTHMA OVER 12 MONTHS" @default.
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- W4367331472 doi "https://doi.org/10.1111/j.1742-1241.2003.tb10584.x" @default.
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