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- W4367366333 abstract "The mussel Mytilus coruscus is an important and very popular seafood in China and widespread along the eastern coast of China. In this study, we investigated the molecular response of mussel gonads to cadmium accumulation at two concentrations (80 and 200 µg/L) for 30 days using ionomics and proteomics techniques. The shrinkage of the cells and moderate hemocytic infiltration were observed in the Cd-treated groups. The strontium, selenium (Se), and zinc contents were significantly altered, and the relationships between iron, copper, Se, manganese, calcium, sodium, and magnesium were also significantly altered. Label-free quantitative proteomics analysis revealed a total of 227 differentially expressed proteins. These proteins were associated with multiple biological processes, including the tricarboxylic acid cycle, structural reorganization of cells, biosynthesis of amino acids, inflammatory response of cells, and tumorigenesis. Nonetheless, our ionomics and proteomics analysis revealed that mussels could partly alleviate the adverse effects of Cd by altering the metal contents and correlations between minerals, thereby enhancing the biosynthesis of some amino acids and activity of antioxidant enzymes. Overall, this study provides an insight into the mechanism underlying Cd toxicity in mussel gonads from a metal and protein perspective." @default.
- W4367366333 created "2023-04-30" @default.
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- W4367366333 date "2023-04-29" @default.
- W4367366333 modified "2023-10-16" @default.
- W4367366333 title "Effect of cadmium in the gonads of mussel (Mytilus coruscus): an ionomics and proteomics study" @default.
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- W4367366333 doi "https://doi.org/10.1007/s11356-023-27208-6" @default.
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