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- W4367367274 abstract "Brillouin light scattering (BLS) spectroscopy is a label-free method of measuring the GHz-frequency viscoelastic properties. The measured longitudinal modulus is acutely sensitive to the degree of hydration, crosslinking, and temperature, which can be indicative of tissue health. As such, performing in situ measurements on humans is particularly desirable for exploring potential clinical translation, however, is not possible with existing designs which are coupled to bench-top microscopes. Here we introduce a robust fiber coupled hand-held BLS probe and demonstrate its reliability for measuring excised human tissue. We verify its accuracy using confocal BLS microscopy and further show that it is possible to distinguish veins, arteries, nerves and muscles based on their BLS-measured viscoelasticity. This provides a necessary first step towards in situ clinical BLS viscoelasticity studies of human tissue." @default.
- W4367367274 created "2023-04-30" @default.
- W4367367274 creator A5044626810 @default.
- W4367367274 date "2023-01-01" @default.
- W4367367274 modified "2023-10-14" @default.
- W4367367274 title "Brillouin scattering spectroscopy for studying human anatomy: Towards <i>in situ</i> mechanical characterization of soft tissue" @default.
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- W4367367274 doi "https://doi.org/10.1051/jeos/2023028" @default.
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