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- W4367367612 abstract "Abstract Malignant ascites in hepatocellular carcinoma is usually a sign of advanced disease and poor prognosis and is also thought to be associated with chronic inflammation mediated by neutrophil extracellular trap networks (NETs). Whereas ozone, a strong oxidant, has significant antibacterial and anti-inflammatory effects, its effectiveness in treating malignant liver ascites is unclear. c Ozone showed significant anti-peritoneal fluid production properties in H22 tumor-bearing mice, and ozone reduced peritoneal fluid production by activating AMPK and up-regulating SR-A phagocytosis damage-associated molecular patterns (DAMPs) to reduce the production of NETs. This suggests that ozone could be used as a new drug for the treatment of malignant ascites in hepatocellular carcinoma." @default.
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- W4367367612 date "2023-04-29" @default.
- W4367367612 modified "2023-09-27" @default.
- W4367367612 title "Mechanism of ozone alleviation of malignant ascites in hepatocellular carcinoma through inhibition of NETs" @default.
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- W4367367612 doi "https://doi.org/10.1101/2023.04.26.538380" @default.
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