Matches in SemOpenAlex for { <https://semopenalex.org/work/W4367604346> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W4367604346 endingPage "7" @default.
- W4367604346 startingPage "1" @default.
- W4367604346 abstract "To report the outcome of locally administered antibiotic-impregnated poloxamer 407 (P407) hydrogel in dogs diagnosed with orthopedic surgical site infections (SSIs) and to identify risk factors for treatment failure.34 client-owned dogs diagnosed with an orthopedic surgical site infection treated with local antibiotic-impregnated P407 hydrogel.Medical records were reviewed of dogs receiving antibiotic-impregnated P407 hydrogel for an active orthopedic SSI between March 2018 and December 2020. The rate of successful infection clearance was calculated. Risk factors for failed treatment were evaluated with statistical analyses.34 dogs met the inclusion criteria. Vancomycin-impregnated P407 hydrogel (20 mg/mL) was implanted in all dogs. The rate of infection clearance was 77%. Each unit increase in the number of surgeries performed at a site before gel implantation decrease the chance of successful infection clearance by 25% (P = .005; unit OR, 0.25; 95% CI, 0.08 to 0.81). Presence of multidrug or methicillin resistance increased risk for treatment failure by 7.69 times (P = .042; OR, 0.13; 95% CI, 0.01 to 1.14). No adverse events related to gel administration were seen.Treatment outcomes were negatively impacted by the presence of multidrug or methicillin resistance and by an increased number of surgeries before gel implantation. Local administration of antibiotic-impregnated P407 hydrogel had a high success rate with no adverse effects in this population. Local antibiotic gel administration may improve treatment outcomes in dogs with complicated SSI." @default.
- W4367604346 created "2023-05-02" @default.
- W4367604346 creator A5040930129 @default.
- W4367604346 creator A5062958469 @default.
- W4367604346 creator A5065507851 @default.
- W4367604346 creator A5088760050 @default.
- W4367604346 creator A5091715354 @default.
- W4367604346 date "2023-05-01" @default.
- W4367604346 modified "2023-09-30" @default.
- W4367604346 title "Number of previous surgeries and antibiotic resistance decreases the success of local administration of antibiotic-impregnated poloxamer 407 hydrogel when managing orthopedic surgical site infections in dogs" @default.
- W4367604346 cites W1930493764 @default.
- W4367604346 doi "https://doi.org/10.2460/javma.23.02.0058" @default.
- W4367604346 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37127278" @default.
- W4367604346 hasPublicationYear "2023" @default.
- W4367604346 type Work @default.
- W4367604346 citedByCount "0" @default.
- W4367604346 crossrefType "journal-article" @default.
- W4367604346 hasAuthorship W4367604346A5040930129 @default.
- W4367604346 hasAuthorship W4367604346A5062958469 @default.
- W4367604346 hasAuthorship W4367604346A5065507851 @default.
- W4367604346 hasAuthorship W4367604346A5088760050 @default.
- W4367604346 hasAuthorship W4367604346A5091715354 @default.
- W4367604346 hasBestOaLocation W43676043461 @default.
- W4367604346 hasConcept C126322002 @default.
- W4367604346 hasConcept C141071460 @default.
- W4367604346 hasConcept C197934379 @default.
- W4367604346 hasConcept C2776093070 @default.
- W4367604346 hasConcept C2778602436 @default.
- W4367604346 hasConcept C2778980435 @default.
- W4367604346 hasConcept C2779489039 @default.
- W4367604346 hasConcept C501593827 @default.
- W4367604346 hasConcept C523546767 @default.
- W4367604346 hasConcept C54355233 @default.
- W4367604346 hasConcept C68312169 @default.
- W4367604346 hasConcept C71924100 @default.
- W4367604346 hasConcept C86803240 @default.
- W4367604346 hasConcept C89423630 @default.
- W4367604346 hasConcept C94665300 @default.
- W4367604346 hasConceptScore W4367604346C126322002 @default.
- W4367604346 hasConceptScore W4367604346C141071460 @default.
- W4367604346 hasConceptScore W4367604346C197934379 @default.
- W4367604346 hasConceptScore W4367604346C2776093070 @default.
- W4367604346 hasConceptScore W4367604346C2778602436 @default.
- W4367604346 hasConceptScore W4367604346C2778980435 @default.
- W4367604346 hasConceptScore W4367604346C2779489039 @default.
- W4367604346 hasConceptScore W4367604346C501593827 @default.
- W4367604346 hasConceptScore W4367604346C523546767 @default.
- W4367604346 hasConceptScore W4367604346C54355233 @default.
- W4367604346 hasConceptScore W4367604346C68312169 @default.
- W4367604346 hasConceptScore W4367604346C71924100 @default.
- W4367604346 hasConceptScore W4367604346C86803240 @default.
- W4367604346 hasConceptScore W4367604346C89423630 @default.
- W4367604346 hasConceptScore W4367604346C94665300 @default.
- W4367604346 hasLocation W43676043461 @default.
- W4367604346 hasLocation W43676043462 @default.
- W4367604346 hasOpenAccess W4367604346 @default.
- W4367604346 hasPrimaryLocation W43676043461 @default.
- W4367604346 hasRelatedWork W1978242588 @default.
- W4367604346 hasRelatedWork W2046258255 @default.
- W4367604346 hasRelatedWork W2168386296 @default.
- W4367604346 hasRelatedWork W2274212671 @default.
- W4367604346 hasRelatedWork W2334913791 @default.
- W4367604346 hasRelatedWork W2970246420 @default.
- W4367604346 hasRelatedWork W3042614407 @default.
- W4367604346 hasRelatedWork W4225389568 @default.
- W4367604346 hasRelatedWork W4296483750 @default.
- W4367604346 hasRelatedWork W942296153 @default.
- W4367604346 isParatext "false" @default.
- W4367604346 isRetracted "false" @default.
- W4367604346 workType "article" @default.